Injectable and Thermosensitive Hydrogel Containing Liraglutide as a Long-Acting Antidiabetic System.

Chen, Yipei; Luan, Jiabin; Shen, Wenjia; Lei, Kewen; Yu, Lin; Ding, Jiandong

Chen, Yipei; Luan, Jiabin; Shen, Wenjia; Lei, Kewen; Yu, Lin; Ding, Jiandong.

Afiliação

Chen Y; State Key Laboratory of Molecular Engineering of Polymers, Department of Macromolecular Science, Fudan University , Shanghai 200433, China.
Luan J; State Key Laboratory of Molecular Engineering of Polymers, Department of Macromolecular Science, Fudan University , Shanghai 200433, China.
Shen W; State Key Laboratory of Molecular Engineering of Polymers, Department of Macromolecular Science, Fudan University , Shanghai 200433, China.
Lei K; State Key Laboratory of Molecular Engineering of Polymers, Department of Macromolecular Science, Fudan University , Shanghai 200433, China.
Yu L; State Key Laboratory of Molecular Engineering of Polymers, Department of Macromolecular Science, Fudan University , Shanghai 200433, China.
Ding J; State Key Laboratory of Molecular Engineering of Polymers, Department of Macromolecular Science, Fudan University , Shanghai 200433, China.

ACS Appl Mater Interfaces ; 8(45): 30703-30713, 2016 Nov 16.

Article em En | MEDLINE | ID: mdl-27786459

Assuntos

Hidrogéis/química; Animais; Diabetes Mellitus Tipo 2; Hipoglicemiantes; Liraglutida; Camundongos; Camundongos Endogâmicos ICR; Poliésteres; Polietilenoglicóis; Temperatura

Palavras-chave

hypoglycemic efficacy; in vivo degradation; liraglutide; sustained drug release; thermosensitive hydrogel; type 2 diabetes mellitus

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Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Hidrogéis Limite: Animals Idioma: En Ano de publicação: 2016 Tipo de documento: Article

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PubMed Links

Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Hidrogéis Limite: Animals Idioma: En Ano de publicação: 2016 Tipo de documento: Article