Evaluation of complications associated with off-label use of recombinant human bone morphogenetic protein-2 (rhBMP-2) in pediatric orthopaedics.

Stiel, Norbert; Hissnauer, Tim N; Rupprecht, Martin; Babin, Kornelia; Schlickewei, Carsten W; Rueger, Johannes M; Stuecker, Ralf; Spiro, Alexander S

Stiel, Norbert; Hissnauer, Tim N; Rupprecht, Martin; Babin, Kornelia; Schlickewei, Carsten W; Rueger, Johannes M; Stuecker, Ralf; Spiro, Alexander S.

Afiliação

Stiel N; Department of Trauma-, Hand-, and Reconstructive Surgery, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Hissnauer TN; Department of Trauma-, Hand-, and Reconstructive Surgery, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Rupprecht M; Department of Pediatric Orthopaedic Surgery, Children's Hospital, Hamburg-Altona, Germany.
Babin K; Department of Orthopaedics, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Schlickewei CW; Department of Pediatric Orthopaedic Surgery, Children's Hospital, Hamburg-Altona, Germany.
Rueger JM; Department of Orthopaedics, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Stuecker R; Department of Trauma-, Hand-, and Reconstructive Surgery, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Spiro AS; Department of Trauma-, Hand-, and Reconstructive Surgery, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.

J Mater Sci Mater Med ; 27(12): 184, 2016 Dec.

Article em En | MEDLINE | ID: mdl-27787808

Assuntos

Proteína Morfogenética Óssea 2/uso terapêutico; Ortopedia/métodos; Fator de Crescimento Transformador beta/uso terapêutico; Adolescente; Criança; Estudos de Coortes; Colágeno/química; Feminino; Humanos; Complicações Intraoperatórias; Vértebras Lombares/cirurgia; Masculino; Neoplasias/metabolismo; Uso Off-Label; Pediatria/métodos; Proteínas Recombinantes/uso terapêutico; Reoperação

Palavras-chave

Bone morphogenetic protein; Cancer; Complications; Pediatrics; Safety; rhBMP-2

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Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Ortopedia / Fator de Crescimento Transformador beta / Proteína Morfogenética Óssea 2 Tipo de estudo: Etiology_studies / Incidence_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limite: Adolescent / Child / Female / Humans / Male Idioma: En Ano de publicação: 2016 Tipo de documento: Article

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