The Third Signal Cytokine Interleukin 12 Rather Than Immune Checkpoint Inhibitors Contributes to the Functional Restoration of Hepatitis D Virus-Specific T Cells.

Schirdewahn, Thomas; Grabowski, Jan; Owusu Sekyere, Solomon; Bremer, Birgit; Wranke, Anika; Lunemann, Sebastian; Schlaphoff, Verena; Kirschner, Janina; Hardtke, Svenja; Manns, Michael Peter; Cornberg, Markus; Wedemeyer, Heiner; Suneetha, Pothakamuri Venkata

Schirdewahn, Thomas; Grabowski, Jan; Owusu Sekyere, Solomon; Bremer, Birgit; Wranke, Anika; Lunemann, Sebastian; Schlaphoff, Verena; Kirschner, Janina; Hardtke, Svenja; Manns, Michael Peter; Cornberg, Markus; Wedemeyer, Heiner; Suneetha, Pothakamuri Venkata.

Afiliação

Schirdewahn T; Department of Gastroenterology, Hepatology and Endocrinology, Hannover Medical School.
Grabowski J; German Center for Infection Research, Partner Site Hannover-Braunschweig.
Owusu Sekyere S; Department of Gastroenterology, Hepatology and Endocrinology, Hannover Medical School.
Bremer B; Department of Gastroenterology, Hepatology and Endocrinology, Hannover Medical School.
Wranke A; Department of Gastroenterology, Hepatology and Endocrinology, Hannover Medical School.
Lunemann S; Department of Gastroenterology, Hepatology and Endocrinology, Hannover Medical School.
Schlaphoff V; Department of Gastroenterology, Hepatology and Endocrinology, Hannover Medical School.
Kirschner J; Department of Gastroenterology, Hepatology and Endocrinology, Hannover Medical School.
Hardtke S; Department of Gastroenterology, Hepatology and Endocrinology, Hannover Medical School.
Manns MP; Department of Gastroenterology, Hepatology and Endocrinology, Hannover Medical School.
Cornberg M; German Center for Infection Research, Partner Site Hannover-Braunschweig.
Wedemeyer H; Department of Gastroenterology, Hepatology and Endocrinology, Hannover Medical School.
Suneetha PV; German Center for Infection Research, Partner Site Hannover-Braunschweig.

J Infect Dis ; 215(1): 139-149, 2017 Jan 01.

Article em En | MEDLINE | ID: mdl-27803174

Assuntos

Linfócitos T CD4-Positivos/imunologia; Linfócitos T CD8-Positivos/imunologia; Hepatite D Crônica/imunologia; Vírus Delta da Hepatite/imunologia; Interleucina-12/administração & dosagem; Interleucina-12/imunologia; Ativação Linfocitária; Adulto; Idoso; Linfócitos T CD4-Positivos/metabolismo; Linfócitos T CD4-Positivos/virologia; Antígenos CD57/imunologia; Linfócitos T CD8-Positivos/metabolismo; Linfócitos T CD8-Positivos/virologia; Antígeno CTLA-4/imunologia; Citocinas/biossíntese; Citomegalovirus/imunologia; Feminino; Hepatite D Crônica/virologia; Vírus Delta da Hepatite/química; Herpesvirus Humano 4/imunologia; Humanos; Masculino; Pessoa de Meia-Idade; Receptor de Morte Celular Programada 1/imunologia; Proteínas com Domínio T/metabolismo; Replicação Viral

Palavras-chave

CD4 T cells; CD57; CD8 T cells; CTLA-4; IL-12; PD-1

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Vírus Delta da Hepatite / Ativação Linfocitária / Linfócitos T CD4-Positivos / Interleucina-12 / Linfócitos T CD8-Positivos / Hepatite D Crônica Limite: Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Ano de publicação: 2017 Tipo de documento: Article

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