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C2-ceramide enhances sorafenib-induced caspase-dependent apoptosis via PI3K/AKT/mTOR and Erk signaling pathways in HCC cells.
Jiang, Shanshan; Wang, Qian; Feng, Meiqing; Li, Jiyang; Guan, Zhongbin; An, Duopeng; Dong, Mengxue; Peng, Yuzhe; Kuerban, Kudelaidi; Ye, Li.
Afiliação
  • Jiang S; Department of Biosynthesis and Key Laboratory of Smart Drug Delivery, Ministry of Education, School of Pharmacy, Fudan University, Shanghai, China.
  • Wang Q; Department of Biosynthesis and Key Laboratory of Smart Drug Delivery, Ministry of Education, School of Pharmacy, Fudan University, Shanghai, China.
  • Feng M; Department of Biosynthesis and Key Laboratory of Smart Drug Delivery, Ministry of Education, School of Pharmacy, Fudan University, Shanghai, China.
  • Li J; Department of Biosynthesis and Key Laboratory of Smart Drug Delivery, Ministry of Education, School of Pharmacy, Fudan University, Shanghai, China.
  • Guan Z; Shanghai Institute For Food And Drug Control, Shanghai, China.
  • An D; Department of Biosynthesis and Key Laboratory of Smart Drug Delivery, Ministry of Education, School of Pharmacy, Fudan University, Shanghai, China.
  • Dong M; Department of Biosynthesis and Key Laboratory of Smart Drug Delivery, Ministry of Education, School of Pharmacy, Fudan University, Shanghai, China.
  • Peng Y; Department of Biosynthesis and Key Laboratory of Smart Drug Delivery, Ministry of Education, School of Pharmacy, Fudan University, Shanghai, China.
  • Kuerban K; Department of Biosynthesis and Key Laboratory of Smart Drug Delivery, Ministry of Education, School of Pharmacy, Fudan University, Shanghai, China.
  • Ye L; Department of Biosynthesis and Key Laboratory of Smart Drug Delivery, Ministry of Education, School of Pharmacy, Fudan University, Shanghai, China. yelil@fudan.edu.cn.
Appl Microbiol Biotechnol ; 101(4): 1535-1546, 2017 Feb.
Article em En | MEDLINE | ID: mdl-27807662

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Compostos de Fenilureia / Apoptose / Niacinamida / Fosfatidilinositol 3-Quinases / Proteínas Proto-Oncogênicas c-akt / Serina-Treonina Quinases TOR Limite: Humans Idioma: En Ano de publicação: 2017 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Compostos de Fenilureia / Apoptose / Niacinamida / Fosfatidilinositol 3-Quinases / Proteínas Proto-Oncogênicas c-akt / Serina-Treonina Quinases TOR Limite: Humans Idioma: En Ano de publicação: 2017 Tipo de documento: Article