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Selective silencing of α-globin by the histone demethylase inhibitor IOX1: a potentially new pathway for treatment of ß-thalassemia.
Mettananda, Sachith; Fisher, Christopher A; Sloane-Stanley, Jackie A; Taylor, Stephen; Oppermann, Udo; Gibbons, Richard J; Higgs, Douglas R.
Afiliação
  • Mettananda S; Medical Research Council (MRC) Molecular Haematology Unit, Weatherall Institute of Molecular Medicine, University of Oxford, UK.
  • Fisher CA; Department of Paediatrics, Faculty of Medicine, University of Kelaniya, Sri Lanka.
  • Sloane-Stanley JA; Medical Research Council (MRC) Molecular Haematology Unit, Weatherall Institute of Molecular Medicine, University of Oxford, UK.
  • Taylor S; Weatherall Institute of Molecular Medicine, University of Oxford, UK.
  • Oppermann U; Weatherall Institute of Molecular Medicine, University of Oxford, UK.
  • Gibbons RJ; Structural Genomics Consortium, University of Oxford, UK.
  • Higgs DR; The Botnar Research Centre, NIHR BRU Oxford, University of Oxford, UK.
Haematologica ; 102(3): e80-e84, 2017 03.
Article em En | MEDLINE | ID: mdl-27810991

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Células Eritroides / Inibidores Enzimáticos / Bibliotecas de Moléculas Pequenas / Alfa-Globinas / Histona Desmetilases / Hidroxiquinolinas Limite: Humans Idioma: En Ano de publicação: 2017 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Células Eritroides / Inibidores Enzimáticos / Bibliotecas de Moléculas Pequenas / Alfa-Globinas / Histona Desmetilases / Hidroxiquinolinas Limite: Humans Idioma: En Ano de publicação: 2017 Tipo de documento: Article