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MIS12/MIND Control at the Kinetochore.

Ladurner, Rene; Straight, Aaron F.
Cell ; 167(4): 889-891, 2016 11 03.
Artigo em Inglês | MEDLINE | ID: mdl-27814517
Kinetochores are complex multiprotein machines that link chromosomes to dynamic microtubules for chromosome segregation. Two studies in Cell reveal the structure of the human MIS12 and budding yeast MIND kinetochore complexes and the regulatory mechanisms that enable them to link chromosomes to microtubules during mitosis.