Inferring Heterozygosity from Ancient and Low Coverage Genomes.

Kousathanas, Athanasios; Leuenberger, Christoph; Link, Vivian; Sell, Christian; Burger, Joachim; Wegmann, Daniel

Kousathanas, Athanasios; Leuenberger, Christoph; Link, Vivian; Sell, Christian; Burger, Joachim; Wegmann, Daniel.

Afiliação

Kousathanas A; Department of Biology and Biochemistry, University of Fribourg, 1700, Switzerland.
Leuenberger C; Statistical and Computational Evolutionary Biology Group, Swiss Institute of Bioinformatics, Fribourg, 1700, Switzerland.
Link V; Department of Mathematics, University of Fribourg, 1200, Switzerland.
Sell C; Department of Biology and Biochemistry, University of Fribourg, 1700, Switzerland.
Burger J; Statistical and Computational Evolutionary Biology Group, Swiss Institute of Bioinformatics, Fribourg, 1700, Switzerland.
Wegmann D; Paleogenetics Group, University of Mainz, 55122, Germany.

Genetics ; 205(1): 317-332, 2017 01.

Article em En | MEDLINE | ID: mdl-27821432

Assuntos

DNA Antigo/análise; Triagem de Portadores Genéticos/métodos; Análise de Sequência de DNA/métodos; Sequência de Bases; Mapeamento Cromossômico/métodos; Variação Genética; Genética Populacional/métodos; Genoma Humano; Heterozigoto; Humanos; Masculino; Software

Palavras-chave

ancient DNA; base recalibration; heterozygosity; low coverage; postmortem damage

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Análise de Sequência de DNA / DNA Antigo / Triagem de Portadores Genéticos Limite: Humans / Male Idioma: En Ano de publicação: 2017 Tipo de documento: Article

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