Binding of galectin-1 to breast cancer cells MCF7 induces apoptosis and inhibition of proliferation in vitro in a 2D- and 3D- cell culture model.

Geiger, Pamina; Mayer, Barbara; Wiest, Irmi; Schulze, Sandra; Jeschke, Udo; Weissenbacher, Tobias

Geiger, Pamina; Mayer, Barbara; Wiest, Irmi; Schulze, Sandra; Jeschke, Udo; Weissenbacher, Tobias.

Afiliação

Geiger P; Department of Obstetrics and Gynecology, LMU Munich-Innenstadt, Maistrasse 11, 80337, München, Germany.
Mayer B; Department of General, Visceral and Transplantation Surgery, Hospital of the LMU Munich, Marchioninistr 15, 81377, Munich, Germany.
Wiest I; Department of Obstetrics and Gynecology, LMU Munich-Innenstadt, Maistrasse 11, 80337, München, Germany.
Schulze S; Department of Obstetrics and Gynecology, LMU Munich-Innenstadt, Maistrasse 11, 80337, München, Germany.
Jeschke U; Department of Obstetrics and Gynecology, LMU Munich-Innenstadt, Maistrasse 11, 80337, München, Germany. udo.jeschke@med.uni-muenchen.de.
Weissenbacher T; Department of Obstetrics and Gynecology, LMU Munich-Innenstadt, Maistrasse 11, 80337, München, Germany.

BMC Cancer ; 16(1): 870, 2016 11 08.

Article em En | MEDLINE | ID: mdl-27825375

Assuntos

Apoptose; Galectina 1/metabolismo; Antígenos Glicosídicos Associados a Tumores/metabolismo; Apoptose/genética; Neoplasias da Mama/metabolismo; Linhagem Celular Tumoral; Proliferação de Células; Feminino; Galectina 1/genética; Expressão Gênica; Humanos; Imuno-Histoquímica; Células MCF-7; Ligação Proteica; Esferoides Celulares; Células Tumorais Cultivadas

Palavras-chave

Apoptosis; Galectin 1; MCF7; Proliferation; Spheroid; Thomsen-Friedenreich

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Apoptose / Galectina 1 Limite: Female / Humans Idioma: En Ano de publicação: 2016 Tipo de documento: Article

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