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Novel Agonist Bioisosteres and Common Structure-Activity Relationships for The Orphan G Protein-Coupled Receptor GPR139.
Shehata, Mohamed A; Nøhr, Anne C; Lissa, Delphine; Bisig, Christoph; Isberg, Vignir; Andersen, Kirsten B; Harpsøe, Kasper; Björkling, Fredrik; Bräuner-Osborne, Hans; Gloriam, David E.
Afiliação
  • Shehata MA; Department of Drug Design and Pharmacology, Faculty of Health and Medical Sciences, University of Copenhagen, Universitetsparken 2, 2100 Copenhagen, Denmark.
  • Nøhr AC; Department of Drug Design and Pharmacology, Faculty of Health and Medical Sciences, University of Copenhagen, Universitetsparken 2, 2100 Copenhagen, Denmark.
  • Lissa D; Department of Drug Design and Pharmacology, Faculty of Health and Medical Sciences, University of Copenhagen, Universitetsparken 2, 2100 Copenhagen, Denmark.
  • Bisig C; Department of Drug Design and Pharmacology, Faculty of Health and Medical Sciences, University of Copenhagen, Universitetsparken 2, 2100 Copenhagen, Denmark.
  • Isberg V; Department of Drug Design and Pharmacology, Faculty of Health and Medical Sciences, University of Copenhagen, Universitetsparken 2, 2100 Copenhagen, Denmark.
  • Andersen KB; Department of Drug Design and Pharmacology, Faculty of Health and Medical Sciences, University of Copenhagen, Universitetsparken 2, 2100 Copenhagen, Denmark.
  • Harpsøe K; Department of Neurodegeneration 1, H. Lundbeck A/S, Ottiliavej 9, 2500 Valby, Denmark.
  • Björkling F; Department of Drug Design and Pharmacology, Faculty of Health and Medical Sciences, University of Copenhagen, Universitetsparken 2, 2100 Copenhagen, Denmark.
  • Bräuner-Osborne H; Department of Drug Design and Pharmacology, Faculty of Health and Medical Sciences, University of Copenhagen, Universitetsparken 2, 2100 Copenhagen, Denmark.
  • Gloriam DE; Department of Drug Design and Pharmacology, Faculty of Health and Medical Sciences, University of Copenhagen, Universitetsparken 2, 2100 Copenhagen, Denmark.
Sci Rep ; 6: 36681, 2016 11 10.
Article em En | MEDLINE | ID: mdl-27830715
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Triazinas / Modelos Moleculares / Receptores Acoplados a Proteínas G / Hidrazinas / Modelos Químicos / Proteínas do Tecido Nervoso Limite: Animals / Humans Idioma: En Ano de publicação: 2016 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Triazinas / Modelos Moleculares / Receptores Acoplados a Proteínas G / Hidrazinas / Modelos Químicos / Proteínas do Tecido Nervoso Limite: Animals / Humans Idioma: En Ano de publicação: 2016 Tipo de documento: Article