Efficient synthesis of [<sup>18</sup> F]FPyME: A new approach for the preparation of maleimide-containing prosthetic groups for the conjugation with thiols.

Cavani, Melanie; Bier, Dirk; Holschbach, Marcus; Coenen, Heinz H

Efficient synthesis of [¹⁸ F]FPyME: A new approach for the preparation of maleimide-containing prosthetic groups for the conjugation with thiols.

Cavani, Melanie; Bier, Dirk; Holschbach, Marcus; Coenen, Heinz H.

Afiliação

Cavani M; Institute of Neuroscience and Medicine, INM-5: Nuclear Chemistry Forschungszentrum Jülich, Jülich, Germany.
Bier D; Institute of Neuroscience and Medicine, INM-5: Nuclear Chemistry Forschungszentrum Jülich, Jülich, Germany.
Holschbach M; Institute of Neuroscience and Medicine, INM-5: Nuclear Chemistry Forschungszentrum Jülich, Jülich, Germany.
Coenen HH; Institute of Neuroscience and Medicine, INM-5: Nuclear Chemistry Forschungszentrum Jülich, Jülich, Germany.

J Labelled Comp Radiopharm ; 60(1): 87-92, 2017 01.

Article em En | MEDLINE | ID: mdl-27862235

Assuntos

Piridinas/síntese química; Compostos Radiofarmacêuticos/síntese química; Succinimidas/síntese química; Maleimidas/química; Compostos de Sulfidrila/química

Palavras-chave

PET chemistry; [18F]FPyME; fluorine-18; maleimide prosthetic group; protein labelling; thiol reactive reagent

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Piridinas / Succinimidas / Compostos Radiofarmacêuticos Idioma: En Ano de publicação: 2017 Tipo de documento: Article

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