Cultured Human Periosteum-Derived Cells Can Differentiate into Osteoblasts in a Perioxisome Proliferator-Activated Receptor Gamma-Mediated Fashion via Bone Morphogenetic Protein signaling.

Chung, Jin-Eun; Park, Jin-Ho; Yun, Jeong-Won; Kang, Young-Hoon; Park, Bong-Wook; Hwang, Sun-Chul; Cho, Yeong-Cheol; Sung, Iel-Yong; Woo, Dong Kyun; Byun, June-Ho

Chung, Jin-Eun; Park, Jin-Ho; Yun, Jeong-Won; Kang, Young-Hoon; Park, Bong-Wook; Hwang, Sun-Chul; Cho, Yeong-Cheol; Sung, Iel-Yong; Woo, Dong Kyun; Byun, June-Ho.

Afiliação

Chung JE; Department of Oral and Maxillofacial Surgery, Gyeongsang National University School of Medicine and Gyeongsang National University Hospital, Institute of Health Sciences, Gyeongsang National University, Jinju 660-702, Republic of Korea.
Park JH; Department of Oral and Maxillofacial Surgery, Gyeongsang National University School of Medicine and Gyeongsang National University Hospital, Institute of Health Sciences, Gyeongsang National University, Jinju 660-702, Republic of Korea.
Yun JW; Department of Oral and Maxillofacial Surgery, Gyeongsang National University School of Medicine and Gyeongsang National University Hospital, Institute of Health Sciences, Gyeongsang National University, Jinju 660-702, Republic of Korea.
Kang YH; Department of Oral and Maxillofacial Surgery, Gyeongsang National University School of Medicine and Gyeongsang National University Hospital, Institute of Health Sciences, Gyeongsang National University, Jinju 660-702, Republic of Korea.
Park BW; Department of Oral and Maxillofacial Surgery, Gyeongsang National University School of Medicine and Gyeongsang National University Hospital, Institute of Health Sciences, Gyeongsang National University, Jinju 660-702, Republic of Korea.
Hwang SC; Department of Orthopaedic Surgery, Institute of Health Sciences, Gyeongsang National University School of Medicine, Jinju, Republic of Korea.
Cho YC; Department of Oral and Maxillofacial Surgery, College of Medicine, Ulsan University Hospital, University of Ulsan, Ulsan, Republic of Korea.
Sung IY; Department of Oral and Maxillofacial Surgery, College of Medicine, Ulsan University Hospital, University of Ulsan, Ulsan, Republic of Korea.
Woo DK; College of Pharmacy and Research Institute of Pharmaceutical Sciences, Gyeongsang National University, Jinju, Republic of Korea.
Byun JH; Department of Oral and Maxillofacial Surgery, Gyeongsang National University School of Medicine and Gyeongsang National University Hospital, Institute of Health Sciences, Gyeongsang National University, Jinju 660-702, Republic of Korea.

Int J Med Sci ; 13(11): 806-818, 2016.

Article em En | MEDLINE | ID: mdl-27877072

Assuntos

Proteína Morfogenética Óssea 2/metabolismo; Diferenciação Celular; Células-Tronco Mesenquimais/fisiologia; Osteoblastos/metabolismo; Osteogênese; PPAR gama/metabolismo; Periósteo/citologia; Proteínas Quinases Ativadas por AMP/antagonistas & inibidores; Adipócitos/metabolismo; Adipogenia; Fosfatase Alcalina/metabolismo; Benzamidas/farmacologia; Células Cultivadas; Subunidade alfa 1 de Fator de Ligação ao Core/metabolismo; Regulação da Expressão Gênica; Humanos; Células-Tronco Mesenquimais/metabolismo; Osteoblastos/fisiologia; PPAR gama/agonistas; PPAR gama/antagonistas & inibidores; Pioglitazona; Cultura Primária de Células; Pirazóis/farmacologia; Piridinas/farmacologia; Pirimidinas/farmacologia; Transdução de Sinais; Tiazolidinedionas/farmacologia

Palavras-chave

BMP signaling; Osteoblastic differentiation; PPARÎ³ agonist; Periosteum-derived cells

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Osteoblastos / Osteogênese / Periósteo / Diferenciação Celular / PPAR gama / Proteína Morfogenética Óssea 2 / Células-Tronco Mesenquimais Limite: Humans Idioma: En Ano de publicação: 2016 Tipo de documento: Article

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