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Nanomolar oligomerization and selective co-aggregation of α-synuclein pathogenic mutants revealed by single-molecule fluorescence.
Sierecki, Emma; Giles, Nichole; Bowden, Quill; Polinkovsky, Mark E; Steinbeck, Janina; Arrioti, Nicholas; Rahman, Diya; Bhumkar, Akshay; Nicovich, Philip R; Ross, Ian; Parton, Robert G; Böcking, Till; Gambin, Yann.
Afiliação
  • Sierecki E; EMBL Australia Node in Single Molecule Science, The University of New South Wales, Sydney NSW 2032 Australia.
  • Giles N; EMBL Australia Node in Single Molecule Science, The University of New South Wales, Sydney NSW 2032 Australia.
  • Bowden Q; EMBL Australia Node in Single Molecule Science, The University of New South Wales, Sydney NSW 2032 Australia.
  • Polinkovsky ME; EMBL Australia Node in Single Molecule Science, The University of New South Wales, Sydney NSW 2032 Australia.
  • Steinbeck J; Institute for Molecular Bioscience, The University of Queensland, St Lucia QLD 4072, Australia.
  • Arrioti N; Institute for Molecular Bioscience, The University of Queensland, St Lucia QLD 4072, Australia.
  • Rahman D; Institute for Molecular Bioscience, The University of Queensland, St Lucia QLD 4072, Australia.
  • Bhumkar A; EMBL Australia Node in Single Molecule Science, The University of New South Wales, Sydney NSW 2032 Australia.
  • Nicovich PR; EMBL Australia Node in Single Molecule Science, The University of New South Wales, Sydney NSW 2032 Australia.
  • Ross I; Institute for Molecular Bioscience, The University of Queensland, St Lucia QLD 4072, Australia.
  • Parton RG; Institute for Molecular Bioscience, The University of Queensland, St Lucia QLD 4072, Australia.
  • Böcking T; EMBL Australia Node in Single Molecule Science, The University of New South Wales, Sydney NSW 2032 Australia.
  • Gambin Y; EMBL Australia Node in Single Molecule Science, The University of New South Wales, Sydney NSW 2032 Australia.
Sci Rep ; 6: 37630, 2016 11 28.
Article em En | MEDLINE | ID: mdl-27892477
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proteínas Mutantes / Alfa-Sinucleína / Agregação Patológica de Proteínas / Agregados Proteicos / Fluorescência / Imagem Individual de Molécula Idioma: En Ano de publicação: 2016 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proteínas Mutantes / Alfa-Sinucleína / Agregação Patológica de Proteínas / Agregados Proteicos / Fluorescência / Imagem Individual de Molécula Idioma: En Ano de publicação: 2016 Tipo de documento: Article