Atmospheric pressure thermal ionization ion source for peptide analysis.
Eur J Mass Spectrom (Chichester)
; 22(6): 307-311, 2016.
Article
em En
| MEDLINE
| ID: mdl-27900860
A novel atmospheric pressure thermal ionization (APTI) ion source was developed for the analysis of liquid samples. The feasibility of the ion source was demonstrated on peptides using two configurations-assisted by hot wire or hot surface. Microalloyed molybdenum, used as a thermal ion- emitter, notably facilitated the formation of multiply-charged ions, but fragmentation products were still observed. Peptide fragmentation accompanying thermal ionization can be used for peptide identification. The described method is promising for studies of biological samples with minimal pre-treatment.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Peptídeos
/
Pressão Atmosférica
/
Mapeamento de Peptídeos
/
Espectrometria de Massas por Ionização por Electrospray
/
Calefação
Tipo de estudo:
Diagnostic_studies
/
Evaluation_studies
/
Prognostic_studies
Idioma:
En
Ano de publicação:
2016
Tipo de documento:
Article