Serum Calcium, Magnesium, Zinc and Copper Levels in Sudanese Women with Preeclampsia.
PLoS One
; 11(12): e0167495, 2016.
Article
em En
| MEDLINE
| ID: mdl-27911936
ABSTRACT
BACKGROUND:
Although the exact pathophysiology of preeclampsia is not fully understood, several elemental micronutrient abnormalities have been suggested to play a contributory role in preeclampsia.AIMS:
To investigate the levels of calcium, magnesium, zinc and copper in women with preeclampsia. SUBJECTS ANDMETHODS:
A case-control study was conducted in Omdurman Maternity Hospital, Sudan, during the period of September through December 2014. The cases were women with preeclampsia while healthy pregnant women were the controls. The medical and obstetrics history was gathered using questionnaires. The serum levels of calcium, magnesium, zinc and copper were measured using atomic absorption spectrophotometer.RESULTS:
There was no significant difference between the two groups in their age, gestational age, parity and body mass index. Zinc and copper levels were not significantly different between the two groups. In comparison with the controls, women with preeclampsia had a significantly lower median (inter-quartile) serum calcium [7.6 (4.0â9.6) vs. 8.1 (10.6â14.2), mg/dl, P = 0.032] and higher levels of magnesium [1.9 (1.4â2.5) vs. 1.4 (1.0â1.9) mg/dl; P = 0.003]. In binary logistic regression, lower calcium (OR = 0.73, 95% CI = 0.56 â 0.95, P = 0.021) and higher magnesium (OR = 5.724, 95% CI = 1.23 â 26.50, P = 0.026) levels were associated with preeclampsia. There were no significant correlations between levels of hemoglobin and these trace elements.CONCLUSION:
The current study showed significant associations between preeclampsia and serum levels of calcium and magnesium.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Pré-Eclâmpsia
/
Zinco
/
Cálcio
/
Cobre
/
Magnésio
Tipo de estudo:
Observational_studies
/
Risk_factors_studies
Limite:
Adult
/
Female
/
Humans
/
Pregnancy
País/Região como assunto:
Africa
Idioma:
En
Ano de publicação:
2016
Tipo de documento:
Article