Your browser doesn't support javascript.
loading
Fragment-Based Approach to the Development of an Orally Bioavailable Lactam Inhibitor of Lipoprotein-Associated Phospholipase A2 (Lp-PLA2).
Woolford, Alison J-A; Day, Philip J; Bénéton, Véronique; Berdini, Valerio; Coyle, Joseph E; Dudit, Yann; Grondin, Pascal; Huet, Pascal; Lee, Lydia Y W; Manas, Eric S; McMenamin, Rachel L; Murray, Christopher W; Page, Lee W; Patel, Vipulkumar K; Potvain, Florent; Rich, Sharna J; Sang, Yingxia; Somers, Don O; Trottet, Lionel; Wan, Zehong; Zhang, Xiaomin.
Afiliação
  • Woolford AJ; Astex Pharmaceuticals , 436 Cambridge Science Park, Milton Road, Cambridge CB4 0QA, United Kingdom.
  • Day PJ; Astex Pharmaceuticals , 436 Cambridge Science Park, Milton Road, Cambridge CB4 0QA, United Kingdom.
  • Bénéton V; Centre de Recherches Francois Hyafil, GlaxoSmithKline , 25-27 Avenue du Québec, Les Ulis, France.
  • Berdini V; Astex Pharmaceuticals , 436 Cambridge Science Park, Milton Road, Cambridge CB4 0QA, United Kingdom.
  • Coyle JE; Astex Pharmaceuticals , 436 Cambridge Science Park, Milton Road, Cambridge CB4 0QA, United Kingdom.
  • Dudit Y; Centre de Recherches Francois Hyafil, GlaxoSmithKline , 25-27 Avenue du Québec, Les Ulis, France.
  • Grondin P; Centre de Recherches Francois Hyafil, GlaxoSmithKline , 25-27 Avenue du Québec, Les Ulis, France.
  • Huet P; Centre de Recherches Francois Hyafil, GlaxoSmithKline , 25-27 Avenue du Québec, Les Ulis, France.
  • Lee LY; Astex Pharmaceuticals , 436 Cambridge Science Park, Milton Road, Cambridge CB4 0QA, United Kingdom.
  • Manas ES; GlaxoSmithKline , 1250 South Collegeville Road, Collegeville, Pennsylvania 19426, United States.
  • McMenamin RL; Astex Pharmaceuticals , 436 Cambridge Science Park, Milton Road, Cambridge CB4 0QA, United Kingdom.
  • Murray CW; Astex Pharmaceuticals , 436 Cambridge Science Park, Milton Road, Cambridge CB4 0QA, United Kingdom.
  • Page LW; Astex Pharmaceuticals , 436 Cambridge Science Park, Milton Road, Cambridge CB4 0QA, United Kingdom.
  • Patel VK; GlaxoSmithKline , Gunnels Wood Road, Stevenage SG1 2NY, United Kingdom.
  • Potvain F; Centre de Recherches Francois Hyafil, GlaxoSmithKline , 25-27 Avenue du Québec, Les Ulis, France.
  • Rich SJ; Astex Pharmaceuticals , 436 Cambridge Science Park, Milton Road, Cambridge CB4 0QA, United Kingdom.
  • Sang Y; Neurodegeneration DPU, GlaxoSmithKline , 898 Halei Road, Zhangjiang Hi-Tech Park, Pudong, Shanghai 201203, China.
  • Somers DO; GlaxoSmithKline , Gunnels Wood Road, Stevenage SG1 2NY, United Kingdom.
  • Trottet L; Centre de Recherches Francois Hyafil, GlaxoSmithKline , 25-27 Avenue du Québec, Les Ulis, France.
  • Wan Z; Neurodegeneration DPU, GlaxoSmithKline , 898 Halei Road, Zhangjiang Hi-Tech Park, Pudong, Shanghai 201203, China.
  • Zhang X; Neurodegeneration DPU, GlaxoSmithKline , 898 Halei Road, Zhangjiang Hi-Tech Park, Pudong, Shanghai 201203, China.
J Med Chem ; 59(23): 10738-10749, 2016 12 08.
Article em En | MEDLINE | ID: mdl-27933945
Assuntos
Buscar no Google
Imprimir
XML
PubMed Links

Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Inibidores Enzimáticos / Lactamas Tipo de estudo: Prognostic_studies / Risk_factors_studies Limite: Animals / Humans Idioma: En Ano de publicação: 2016 Tipo de documento: Article
Buscar no Google
Imprimir
XML
PubMed Links

Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Inibidores Enzimáticos / Lactamas Tipo de estudo: Prognostic_studies / Risk_factors_studies Limite: Animals / Humans Idioma: En Ano de publicação: 2016 Tipo de documento: Article