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Pharmacokinetics and pharmacodynamics of intrathecally administered Xen2174, a synthetic conopeptide with norepinephrine reuptake inhibitor and analgesic properties.
Okkerse, Pieter; Hay, Justin L; Sitsen, Elske; Dahan, Albert; Klaassen, Erica; Houghton, William; Groeneveld, Geert Jan.
Afiliação
  • Okkerse P; Centre for Human Drug Research (CHDR), Leiden, The Netherlands.
  • Hay JL; Centre for Human Drug Research (CHDR), Leiden, The Netherlands.
  • Sitsen E; Leiden University Medical Center (LUMC), Leiden, The Netherlands.
  • Dahan A; Leiden University Medical Center (LUMC), Leiden, The Netherlands.
  • Klaassen E; Centre for Human Drug Research (CHDR), Leiden, The Netherlands.
  • Houghton W; Xenome Ltd, Indooroopilly, QLD, Australia.
  • Groeneveld GJ; Centre for Human Drug Research (CHDR), Leiden, The Netherlands.
Br J Clin Pharmacol ; 83(4): 751-763, 2017 04.
Article em En | MEDLINE | ID: mdl-27987228

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Dor / Peptídeos / Norepinefrina / Analgésicos Tipo de estudo: Clinical_trials Limite: Adolescent / Adult / Female / Humans / Male / Middle aged Idioma: En Ano de publicação: 2017 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Dor / Peptídeos / Norepinefrina / Analgésicos Tipo de estudo: Clinical_trials Limite: Adolescent / Adult / Female / Humans / Male / Middle aged Idioma: En Ano de publicação: 2017 Tipo de documento: Article