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Novel splice-switching oligonucleotide promotes BRCA1 aberrant splicing and susceptibility to PARP inhibitor action.
Smith, Lindsay D; Leme de Calais, Flávia; Raponi, Michela; Mellone, Massimiliano; Buratti, Emanuele; Blaydes, Jeremy P; Baralle, Diana.
Afiliação
  • Smith LD; Human Development and Health, Faculty of Medicine, University of Southampton, Southampton, UK.
  • Leme de Calais F; Cancer Sciences Unit, Faculty of Medicine, University of Southampton, Southampton, UK.
  • Raponi M; Human Development and Health, Faculty of Medicine, University of Southampton, Southampton, UK.
  • Mellone M; Human Development and Health, Faculty of Medicine, University of Southampton, Southampton, UK.
  • Buratti E; Cancer Sciences Unit, Faculty of Medicine, University of Southampton, Southampton, UK.
  • Blaydes JP; International Centre for Genetic Engineering and Biotechnology, Padriciano, 99 34149, Trieste, Italy.
  • Baralle D; Cancer Sciences Unit, Faculty of Medicine, University of Southampton, Southampton, UK.
Int J Cancer ; 140(7): 1564-1570, 2017 04 01.
Article em En | MEDLINE | ID: mdl-27997688

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Oligonucleotídeos / Neoplasias da Mama / Processamento Alternativo / Genes BRCA1 / Inibidores de Poli(ADP-Ribose) Polimerases Limite: Female / Humans Idioma: En Ano de publicação: 2017 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Oligonucleotídeos / Neoplasias da Mama / Processamento Alternativo / Genes BRCA1 / Inibidores de Poli(ADP-Ribose) Polimerases Limite: Female / Humans Idioma: En Ano de publicação: 2017 Tipo de documento: Article