[11 beta-hydroxylation of 16 alpha-methyl-Reichstein's compound S 21-acetate by Curvularia lunata].
Wei Sheng Wu Xue Bao
; 29(1): 68-71, 1989 Feb.
Article
em Zh
| MEDLINE
| ID: mdl-2800540
ABSTRACT
The conversion of 16 alpha-methyl-Reichstein's compound S 21-acetate (I) to 16 alpha-methyl-hydrocortisone (II) by the mycelium Curvularia lunata AS3.4381 was studied. Maximal 11 beta-hydroxylating activity of the mycelium was found during cultivation of the microorganism by 24h. Inhibition of the ethanol to the 11 beta-hydroxylating activity was obvious. The yield of 55.4% (II) (W/W) could be achieved during conversion of 0.15% substrate at 72 h.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Hidrocortisona
/
Fungos Mitospóricos
Idioma:
Zh
Ano de publicação:
1989
Tipo de documento:
Article