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Microphase separation in solid lipid dosage forms as the cause of drug release instability.
Lopes, Diogo Gomes; Koutsamanis, Ioannis; Becker, Karin; Scheibelhofer, Otto; Laggner, Peter; Haack, Detlev; Stehr, Michael; Zimmer, Andreas; Salar-Behzadi, Sharareh.
Afiliação
  • Lopes DG; Research Center Pharmaceutical Engineering GmbH, Graz, Austria; Institute of Pharmaceutical Science, Department of Pharmaceutical Technology, University of Graz, Austria.
  • Koutsamanis I; Research Center Pharmaceutical Engineering GmbH, Graz, Austria; Institute of Pharmaceutical Science, Department of Pharmaceutical Technology, University of Graz, Austria.
  • Becker K; Institute of Pharmaceutical Science, Department of Pharmaceutical Technology, University of Graz, Austria.
  • Scheibelhofer O; Research Center Pharmaceutical Engineering GmbH, Graz, Austria.
  • Laggner P; Research Center Pharmaceutical Engineering GmbH, Graz, Austria; Bruker AXS GmbH, Graz, Austria.
  • Haack D; Hermes Arzneimittel GmbH, Großhesselohe, Germany.
  • Stehr M; IOI Oleo GmbH, Witten, Germany.
  • Zimmer A; Institute of Pharmaceutical Science, Department of Pharmaceutical Technology, University of Graz, Austria.
  • Salar-Behzadi S; Research Center Pharmaceutical Engineering GmbH, Graz, Austria. Electronic address: sharareh.salar-behzadi@rcpe.at.
Int J Pharm ; 517(1-2): 403-412, 2017 Jan 30.
Article em En | MEDLINE | ID: mdl-28007547
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Polissorbatos / Acetilcisteína / Triglicerídeos / Estabilidade de Medicamentos / Liberação Controlada de Fármacos Idioma: En Ano de publicação: 2017 Tipo de documento: Article
Texto completo
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PubMed Links
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Polissorbatos / Acetilcisteína / Triglicerídeos / Estabilidade de Medicamentos / Liberação Controlada de Fármacos Idioma: En Ano de publicação: 2017 Tipo de documento: Article