Modelling autonomous oscillations in the human pupil light reflex using non-linear delay-differential equations.
Bull Math Biol
; 51(5): 605-24, 1989.
Article
em En
| MEDLINE
| ID: mdl-2804468
Neurophysiological and anatomical observations are used to derive a non-linear delay-differential equation for the pupil light reflex with negative feedback. As the gain or the time delay in the reflex is increased, a supercritical Hopf bifurcation occurs from a stable fixed point to a stable limit cycle oscillation in pupil area. A Hopf bifurcation analysis is used to determine the conditions for instability and the period and amplitude of these oscillations. The more complex waveforms typical of the occurrence of higher order bifurcations were not seen in numerical simulations of the model. This model provides a general framework to study the different types of dynamical behaviors which can be produced by the pupil light reflex, e.g. edge-light pupil cycling.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Reflexo Pupilar
/
Modelos Teóricos
Limite:
Humans
Idioma:
En
Ano de publicação:
1989
Tipo de documento:
Article