Fingerprinting of strong spermatogenesis steroidal saponins in male flowers of Phoenix dactylifera (Date Palm) by LC-ESI-MS.
Nat Prod Res
; 31(17): 2024-2031, 2017 Sep.
Article
em En
| MEDLINE
| ID: mdl-28049352
ABSTRACT
A fingerprint of steroid saponins, the major constituent in 80% methanolic fraction from the male flowers of Phoenix dactylifera has been established. Under ESI-MS/MS conditions, the fragmentation patterns of [M - H]- ions exclusively displayed signals corresponding to the cleavage of the glycosidic bonds, thus allowing a rapid identification of 21 steroidal saponins. Moreover, two unique among them conjugated with histidine were detected by LC-ESI (-)-MS and DFT and were given tentative names of 3-o-histidine-26-o-hexosyl-dioscin and 3-o-histidine-26-o-dihexosyl-hydroxydioscin. Their steroidal saponins exhibited a significant improvement of the sperm cells count, motility and viability in male rats. These effects could be attributed to enhancing the levels of sex hormones.
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Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Saponinas
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Espermatogênese
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Phoeniceae
Limite:
Animals
Idioma:
En
Ano de publicação:
2017
Tipo de documento:
Article