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ERK activation and autophagy impairment are central mediators of irinotecan-induced steatohepatitis.
Mahli, Abdo; Saugspier, Michael; Koch, Andreas; Sommer, Judith; Dietrich, Peter; Lee, Seren; Thasler, Reinhard; Schulze-Luehrmann, Jan; Luehrmann, Anja; Thasler, Wolfgang Erwin; Müller, Martina; Bosserhoff, Anja; Hellerbrand, Claus.
Afiliação
  • Mahli A; Department of Internal Medicine I, University Hospital Regensburg, Regensburg, Germany.
  • Saugspier M; Institute of Biochemistry (Emil-Fischer Zentrum), Friedrich-Alexander University Erlangen-Nürnberg, Erlangen, Germany.
  • Koch A; Department of Internal Medicine I, University Hospital Regensburg, Regensburg, Germany.
  • Sommer J; Department of Internal Medicine I, University Hospital Regensburg, Regensburg, Germany.
  • Dietrich P; Institute of Biochemistry (Emil-Fischer Zentrum), Friedrich-Alexander University Erlangen-Nürnberg, Erlangen, Germany.
  • Lee S; Department of Internal Medicine I, University Hospital Regensburg, Regensburg, Germany.
  • Thasler R; Institute of Biochemistry (Emil-Fischer Zentrum), Friedrich-Alexander University Erlangen-Nürnberg, Erlangen, Germany.
  • Schulze-Luehrmann J; Institute of Biochemistry (Emil-Fischer Zentrum), Friedrich-Alexander University Erlangen-Nürnberg, Erlangen, Germany.
  • Luehrmann A; Biobank o.b. HTCR, Department of General Visceral- and Transplantation Surgery, Ludwig-Maximilians-University Munich, Munich, Germany.
  • Thasler WE; Biobank o.b. HTCR, Department of General Visceral- and Transplantation Surgery, Ludwig-Maximilians-University Munich, Munich, Germany.
  • Müller M; Mikrobiologisches Institut - Klinische Mikrobiologie, Immunologie und Hygiene, Universitätsklinikum Erlangen, Friedrich-Alexander-Universität (FAU) Erlangen-Nürnberg, Erlangen, Germany.
  • Bosserhoff A; Mikrobiologisches Institut - Klinische Mikrobiologie, Immunologie und Hygiene, Universitätsklinikum Erlangen, Friedrich-Alexander-Universität (FAU) Erlangen-Nürnberg, Erlangen, Germany.
  • Hellerbrand C; Biobank o.b. HTCR, Department of General Visceral- and Transplantation Surgery, Ludwig-Maximilians-University Munich, Munich, Germany.
Gut ; 67(4): 746-756, 2018 04.
Article em En | MEDLINE | ID: mdl-28053052
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Autofagia / Cuidados Pré-Operatórios / Camptotecina / Sistema de Sinalização das MAP Quinases / Hepatócitos / Fígado Gorduroso / Antineoplásicos Fitogênicos Limite: Animals / Humans Idioma: En Ano de publicação: 2018 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Autofagia / Cuidados Pré-Operatórios / Camptotecina / Sistema de Sinalização das MAP Quinases / Hepatócitos / Fígado Gorduroso / Antineoplásicos Fitogênicos Limite: Animals / Humans Idioma: En Ano de publicação: 2018 Tipo de documento: Article