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SOX2 promotes lineage plasticity and antiandrogen resistance in TP53- and RB1-deficient prostate cancer.
Mu, Ping; Zhang, Zeda; Benelli, Matteo; Karthaus, Wouter R; Hoover, Elizabeth; Chen, Chi-Chao; Wongvipat, John; Ku, Sheng-Yu; Gao, Dong; Cao, Zhen; Shah, Neel; Adams, Elizabeth J; Abida, Wassim; Watson, Philip A; Prandi, Davide; Huang, Chun-Hao; de Stanchina, Elisa; Lowe, Scott W; Ellis, Leigh; Beltran, Himisha; Rubin, Mark A; Goodrich, David W; Demichelis, Francesca; Sawyers, Charles L.
Afiliação
  • Mu P; Human Oncology and Pathology Program, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York, NY 10065, USA.
  • Zhang Z; Human Oncology and Pathology Program, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York, NY 10065, USA.
  • Benelli M; Louis V. Gerstner, Jr. Graduate School of Biomedical Sciences, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.
  • Karthaus WR; Centre for Integrative Biology, University of Trento, Trento, Italy.
  • Hoover E; Human Oncology and Pathology Program, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York, NY 10065, USA.
  • Chen CC; Human Oncology and Pathology Program, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York, NY 10065, USA.
  • Wongvipat J; Cancer Biology and Genetics Program, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York, NY 10065, USA.
  • Ku SY; Weill Cornell Graduate School of Medical Sciences of Cornell University, New York, NY 10021, USA.
  • Gao D; Human Oncology and Pathology Program, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York, NY 10065, USA.
  • Cao Z; Department of Pharmacology and Therapeutics, Roswell Park Cancer Institute, New York, NY 14263, USA.
  • Shah N; Human Oncology and Pathology Program, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York, NY 10065, USA.
  • Adams EJ; Human Oncology and Pathology Program, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York, NY 10065, USA.
  • Abida W; Weill Cornell Graduate School of Medical Sciences of Cornell University, New York, NY 10021, USA.
  • Watson PA; Human Oncology and Pathology Program, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York, NY 10065, USA.
  • Prandi D; Louis V. Gerstner, Jr. Graduate School of Biomedical Sciences, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.
  • Huang CH; Human Oncology and Pathology Program, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York, NY 10065, USA.
  • de Stanchina E; Human Oncology and Pathology Program, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York, NY 10065, USA.
  • Lowe SW; Human Oncology and Pathology Program, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York, NY 10065, USA.
  • Ellis L; Centre for Integrative Biology, University of Trento, Trento, Italy.
  • Beltran H; Cancer Biology and Genetics Program, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York, NY 10065, USA.
  • Rubin MA; Weill Cornell Graduate School of Medical Sciences of Cornell University, New York, NY 10021, USA.
  • Goodrich DW; Department of Molecular Pharmacology, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York, NY 10065, USA.
  • Demichelis F; Cancer Biology and Genetics Program, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York, NY 10065, USA.
  • Sawyers CL; Weill Cornell Graduate School of Medical Sciences of Cornell University, New York, NY 10021, USA.
Science ; 355(6320): 84-88, 2017 01 06.
Article em En | MEDLINE | ID: mdl-28059768

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Feniltioidantoína / Neoplasias da Próstata / Proteína Supressora de Tumor p53 / Ubiquitina-Proteína Ligases / Fatores de Transcrição SOXB1 / Proteínas de Ligação a Retinoblastoma / Antagonistas de Androgênios Tipo de estudo: Prognostic_studies Limite: Humans / Male Idioma: En Ano de publicação: 2017 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Feniltioidantoína / Neoplasias da Próstata / Proteína Supressora de Tumor p53 / Ubiquitina-Proteína Ligases / Fatores de Transcrição SOXB1 / Proteínas de Ligação a Retinoblastoma / Antagonistas de Androgênios Tipo de estudo: Prognostic_studies Limite: Humans / Male Idioma: En Ano de publicação: 2017 Tipo de documento: Article