Objectively measured sedentary behavior and brain volumetric measurements in multiple sclerosis.
Neurodegener Dis Manag
; 7(1): 31-37, 2017 Feb.
Article
em En
| MEDLINE
| ID: mdl-28074683
ABSTRACT
AIM:
This study examined the association between sedentary behavior patterns and whole brain gray matter (GM), white matter (WM) and subcortical GM structures in persons with multiple sclerosis (MS).METHODS:
36 persons with MS wore an accelerometer and underwent a brain MRI. Whole brain GM and WM and deep GM structures were calculated from 3D T1-weighted structural brain images.RESULTS:
There were statistically significant (p < 0.01) and moderate or large associations between number of sedentary bouts/day and brain volume measures. The primary result was a consistent negative association between number of sedentary bouts/day and whole brain GM and WM, and deep GM structures.CONCLUSION:
We provide novel evidence for decreased brain volume as a correlate of a sedentary behavior pattern in persons with MS.Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Encéfalo
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Comportamento Sedentário
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Esclerose Múltipla
Limite:
Humans
Idioma:
En
Ano de publicação:
2017
Tipo de documento:
Article