Protective Effects of Emodin-Induced Neutrophil Apoptosis via the Ca<sup>2+</sup>-Caspase 12 Pathway against SIRS in Rats with Severe Acute Pancreatitis.

Wang, Gui-Jun; Wang, Yue; Teng, Yong-Sheng; Sun, Fa-Lv; Xiang, Hong; Liu, Jian-Jun; Xia, Shi-Lin; Zhang, Gui-Xin; Chen, Hai-Long; Shang, Dong

Protective Effects of Emodin-Induced Neutrophil Apoptosis via the Ca²⁺-Caspase 12 Pathway against SIRS in Rats with Severe Acute Pancreatitis.

Wang, Gui-Jun; Wang, Yue; Teng, Yong-Sheng; Sun, Fa-Lv; Xiang, Hong; Liu, Jian-Jun; Xia, Shi-Lin; Zhang, Gui-Xin; Chen, Hai-Long; Shang, Dong.

Afiliação

Wang GJ; Pancreaticobiliary Centre, Department of General Surgery, The First Affiliated Hospital of Dalian Medical University, Dalian, Liaoning 116044, China.
Wang Y; Pancreaticobiliary Centre, Department of General Surgery, The First Affiliated Hospital of Dalian Medical University, Dalian, Liaoning 116044, China.
Teng YS; College of Integrative Medicine, Dalian Medical University, Dalian, Liaoning 116044, China.
Sun FL; College of Integrative Medicine, Dalian Medical University, Dalian, Liaoning 116044, China.
Xiang H; College of Integrative Medicine, Dalian Medical University, Dalian, Liaoning 116044, China.
Liu JJ; Clinical Laboratory of Integrative Medicine, The First Affiliated Hospital of Dalian Medical University, Dalian, Liaoning 116044, China.
Xia SL; Clinical Laboratory of Integrative Medicine, The First Affiliated Hospital of Dalian Medical University, Dalian, Liaoning 116044, China.
Zhang GX; Pancreaticobiliary Centre, Department of General Surgery, The First Affiliated Hospital of Dalian Medical University, Dalian, Liaoning 116044, China.
Chen HL; Pancreaticobiliary Centre, Department of General Surgery, The First Affiliated Hospital of Dalian Medical University, Dalian, Liaoning 116044, China.
Shang D; Pancreaticobiliary Centre, Department of General Surgery, The First Affiliated Hospital of Dalian Medical University, Dalian, Liaoning 116044, China.

Biomed Res Int ; 2016: 1736024, 2016.

Article em En | MEDLINE | ID: mdl-28078280

Assuntos

Caspase 12/biossíntese; Emodina/administração & dosagem; Inflamação/tratamento farmacológico; Pancreatite/tratamento farmacológico; Acrilatos/administração & dosagem; Animais; Apoptose/efeitos dos fármacos; Cálcio/metabolismo; Calpaína/antagonistas & inibidores; Calpaína/biossíntese; Caspase 12/genética; Caspase 3/biossíntese; Caspase 3/genética; Regulação da Expressão Gênica/efeitos dos fármacos; Humanos; Inflamação/genética; Inflamação/patologia; Neutrófilos/efeitos dos fármacos; Pancreatite/genética; Pancreatite/patologia; Ratos; Transdução de Sinais/efeitos dos fármacos

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Pancreatite / Emodina / Caspase 12 / Inflamação Limite: Animals / Humans Idioma: En Ano de publicação: 2016 Tipo de documento: Article

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google