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DNA Damage Signaling Instructs Polyploid Macrophage Fate in Granulomas.
Herrtwich, Laura; Nanda, Indrajit; Evangelou, Konstantinos; Nikolova, Teodora; Horn, Veronika; Erny, Daniel; Stefanowski, Jonathan; Rogell, Leif; Klein, Claudius; Gharun, Kourosh; Follo, Marie; Seidl, Maximilian; Kremer, Bernhard; Münke, Nikolas; Senges, Julia; Fliegauf, Manfred; Aschman, Tom; Pfeifer, Dietmar; Sarrazin, Sandrine; Sieweke, Michael H; Wagner, Dirk; Dierks, Christine; Haaf, Thomas; Ness, Thomas; Zaiss, Mario M; Voll, Reinhard E; Deshmukh, Sachin D; Prinz, Marco; Goldmann, Torsten; Hölscher, Christoph; Hauser, Anja E; Lopez-Contreras, Andres J; Grün, Dominic; Gorgoulis, Vassilis; Diefenbach, Andreas; Henneke, Philipp; Triantafyllopoulou, Antigoni.
Afiliação
  • Herrtwich L; Department of Rheumatology and Clinical Immunology, Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, 79106 Freiburg, Germany; Center of Chronic Immunodeficiency, Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, 79106 Freiburg,
  • Nanda I; Institute of Human Genetics, Biozentrum, Am Hubland, 97074 Würzburg, Germany.
  • Evangelou K; Molecular Carcinogenesis Group, Department of Histology and Embryology, School of Medicine, National and Kapodistrian University of Athens, 115 27 Athens, Greece.
  • Nikolova T; Institute of Toxicology, University Medical Center Mainz, 55131 Mainz, Germany.
  • Horn V; Department of Rheumatology and Clinical Immunology, Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, 79106 Freiburg, Germany.
  • Sagar; Max Planck Institute of Immunobiology and Epigenetics, 79108 Freiburg, Germany.
  • Erny D; Institute of Neuropathology, Medical Center, University of Freiburg, Faculty of Medicine, University of Freiburg, 79106 Freiburg, Germany.
  • Stefanowski J; Immune Dynamics, Charité Universitätsmedizin and Deutsches Rheumaforschungszentrum, 10117 Berlin, Germany.
  • Rogell L; Max Planck Institute of Immunobiology and Epigenetics, 79108 Freiburg, Germany; Institute of Medical Microbiology and Hygiene, University of Mainz Medical Center, 55131 Mainz, Germany; Research Center for Immunology and Immunotherapy, University of Mainz Medical Center, 55131 Mainz, Germany.
  • Klein C; Department of Medicine I, Medical Center, University of Freiburg, Faculty of Medicine, University of Freiburg, 79106 Freiburg, Germany.
  • Gharun K; Center of Chronic Immunodeficiency, Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, 79106 Freiburg, Germany.
  • Follo M; Department of Medicine I, Medical Center, University of Freiburg, Faculty of Medicine, University of Freiburg, 79106 Freiburg, Germany.
  • Seidl M; Department of Pathology, Medical Center, University of Freiburg, Faculty of Medicine, University of Freiburg, 79106 Freiburg, Germany.
  • Kremer B; Center of Chronic Immunodeficiency, Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, 79106 Freiburg, Germany.
  • Münke N; Center of Chronic Immunodeficiency, Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, 79106 Freiburg, Germany.
  • Senges J; Center of Chronic Immunodeficiency, Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, 79106 Freiburg, Germany.
  • Fliegauf M; Center of Chronic Immunodeficiency, Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, 79106 Freiburg, Germany.
  • Aschman T; Department of Rheumatology and Clinical Immunology, Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, 79106 Freiburg, Germany.
  • Pfeifer D; Department of Medicine I, Medical Center, University of Freiburg, Faculty of Medicine, University of Freiburg, 79106 Freiburg, Germany.
  • Sarrazin S; Aix-Marseille Univ, CNRS, INSERM, CIML, 13288 Marseille, France.
  • Sieweke MH; Aix-Marseille Univ, CNRS, INSERM, CIML, 13288 Marseille, France; Max-Delbrück-Centrum für Molekulare Medizin in der Helmholtzgemeinschaft (MDC), 13125 Berlin, Germany.
  • Wagner D; Center of Chronic Immunodeficiency, Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, 79106 Freiburg, Germany; Division of Infectious Diseases, Department of Internal Medicine 2, Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg,
  • Dierks C; Department of Medicine I, Medical Center, University of Freiburg, Faculty of Medicine, University of Freiburg, 79106 Freiburg, Germany.
  • Haaf T; Institute of Human Genetics, Biozentrum, Am Hubland, 97074 Würzburg, Germany.
  • Ness T; Eye Center, Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, 79106 Freiburg, Germany.
  • Zaiss MM; Department of Internal Medicine 3, Rheumatology and Immunology, University of Erlangen-Nuremberg, 91054 Erlangen, Germany.
  • Voll RE; Department of Rheumatology and Clinical Immunology, Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, 79106 Freiburg, Germany.
  • Deshmukh SD; Center for Sepsis Control and Care, Jena University Hospital, 07747 Jena, Germany.
  • Prinz M; Institute of Neuropathology, Medical Center, University of Freiburg, Faculty of Medicine, University of Freiburg, 79106 Freiburg, Germany; BIOSS Centre for Biological Signalling Studies, University of Freiburg, 79106 Freiburg, Germany.
  • Goldmann T; Department of Pathology, Schleswig-Holstein University Hospital, Campus Lübeck and Research Center Borstel, 23845 Borstel, Germany.
  • Hölscher C; Division of Infection Immunology, Research Center Borstel, 23845 Borstel, Germany; Cluster of Excellence, Inflammation at Interfaces (Borstel-Kiel-Lübeck-Plön), 24118 Kiel, Germany; German Centre for Infection Research, 23845 Borstel, Germany.
  • Hauser AE; Immune Dynamics, Charité Universitätsmedizin and Deutsches Rheumaforschungszentrum, 10117 Berlin, Germany.
  • Lopez-Contreras AJ; Center for Chromosome Stability, Department of Cellular and Molecular Medicine, Panum Institute, University of Copenhagen, 2200 Copenhagen N, Denmark.
  • Grün D; Max Planck Institute of Immunobiology and Epigenetics, 79108 Freiburg, Germany.
  • Gorgoulis V; Molecular Carcinogenesis Group, Department of Histology and Embryology, School of Medicine, National and Kapodistrian University of Athens, 115 27 Athens, Greece; Faculty Institute of Cancer Sciences, Manchester Academic Health Sciences Centre, University of Manchester, Manchester M20 4QL, UK; Biome
  • Diefenbach A; Institute of Medical Microbiology and Hygiene, University of Mainz Medical Center, 55131 Mainz, Germany; Research Center for Immunology and Immunotherapy, University of Mainz Medical Center, 55131 Mainz, Germany. Electronic address: diefenbach@uni-mainz.de.
  • Henneke P; Center of Chronic Immunodeficiency, Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, 79106 Freiburg, Germany; Center for Pediatrics and Adolescent Medicine, Medical Center, University of Freiburg, Faculty of Medicine, University of Freiburg, 79106 Freiburg, Germa
  • Triantafyllopoulou A; Department of Rheumatology and Clinical Immunology, Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, 79106 Freiburg, Germany; Center of Chronic Immunodeficiency, Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, 79106 Freiburg,
Cell ; 167(5): 1264-1280.e18, 2016 11 17.
Article em En | MEDLINE | ID: mdl-28084216
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Dano ao DNA / Granuloma / Macrófagos / Mycobacterium tuberculosis Limite: Animals / Humans Idioma: En Ano de publicação: 2016 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Dano ao DNA / Granuloma / Macrófagos / Mycobacterium tuberculosis Limite: Animals / Humans Idioma: En Ano de publicação: 2016 Tipo de documento: Article