Hepatitis C Virus-Induced Monocyte Differentiation Into Polarized M2 Macrophages Promotes Stellate Cell Activation via TGF-ß.

Saha, Banishree; Kodys, Karen; Szabo, Gyongyi

Hepatitis C Virus-Induced Monocyte Differentiation Into Polarized M2 Macrophages Promotes Stellate Cell Activation via TGF-ß.

Saha, Banishree; Kodys, Karen; Szabo, Gyongyi.

Afiliação

Saha B; Department of Medicine, University of Massachusetts Medical School, Worcester, Massachusetts.
Kodys K; Department of Medicine, University of Massachusetts Medical School, Worcester, Massachusetts.
Szabo G; Department of Medicine, University of Massachusetts Medical School, Worcester, Massachusetts.

Cell Mol Gastroenterol Hepatol ; 2(3): 302-316.e8, 2016 May.

Article em En | MEDLINE | ID: mdl-28090562

Palavras-chave

APC, antigen-presenting cell; Biomarkers; CD206; COL, collagen; Collagen; FITC, fluorescein isothiocyanate; Fibrocytes; HCV, hepatitis C virus; HSC, hepatic stellate cell; Huh7.5/JFH-1, Huh7.5 cells infected with JFH-1 (HCV); IL, interleukin; IL1RA, IL1-receptor antagonist; JFH-1, Japanese fulminant hepatitis-1; MFI, mean fluorescence intensity; MΦ, macrophage; NEAA, nonessential amino acid; PBMC, peripheral blood mononuclear cell; PE, Phycoerythrin; TGF, transforming growth factor; TIMP, tissue inhibitor of metalloproteinase; TNF, tumor necrosis factor; mRNA, messenger RNA; α-SMA, α-smooth muscle actin

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Tipo de estudo: Prognostic_studies Idioma: En Ano de publicação: 2016 Tipo de documento: Article

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Tipo de estudo: Prognostic_studies Idioma: En Ano de publicação: 2016 Tipo de documento: Article