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Chronic signaling via the metabolic checkpoint kinase mTORC1 induces macrophage granuloma formation and marks sarcoidosis progression.
Linke, Monika; Pham, Ha Thi Thanh; Katholnig, Karl; Schnöller, Thomas; Miller, Anne; Demel, Florian; Schütz, Birgit; Rosner, Margit; Kovacic, Boris; Sukhbaatar, Nyamdelger; Niederreiter, Birgit; Blüml, Stephan; Kuess, Peter; Sexl, Veronika; Müller, Mathias; Mikula, Mario; Weckwerth, Wolfram; Haschemi, Arvand; Susani, Martin; Hengstschläger, Markus; Gambello, Michael J; Weichhart, Thomas.
Afiliação
  • Linke M; Center of Pathobiochemistry and Genetics, Institute of Medical Genetics, Medical University of Vienna, Vienna, Austria.
  • Pham HT; Center of Pathobiochemistry and Genetics, Institute of Medical Genetics, Medical University of Vienna, Vienna, Austria.
  • Katholnig K; Center of Pathobiochemistry and Genetics, Institute of Medical Genetics, Medical University of Vienna, Vienna, Austria.
  • Schnöller T; Center of Pathobiochemistry and Genetics, Institute of Medical Genetics, Medical University of Vienna, Vienna, Austria.
  • Miller A; Department of Laboratory Medicine (KILM), Medical University of Vienna, Vienna, Austria.
  • Demel F; Center of Pathobiochemistry and Genetics, Institute of Medical Genetics, Medical University of Vienna, Vienna, Austria.
  • Schütz B; Center of Pathobiochemistry and Genetics, Institute of Medical Genetics, Medical University of Vienna, Vienna, Austria.
  • Rosner M; Center of Pathobiochemistry and Genetics, Institute of Medical Genetics, Medical University of Vienna, Vienna, Austria.
  • Kovacic B; Center of Pathobiochemistry and Genetics, Institute of Medical Genetics, Medical University of Vienna, Vienna, Austria.
  • Sukhbaatar N; Center of Pathobiochemistry and Genetics, Institute of Medical Genetics, Medical University of Vienna, Vienna, Austria.
  • Niederreiter B; Division of Rheumatology, Department of Internal Medicine III, Medical University of Vienna, Vienna, Austria.
  • Blüml S; Division of Rheumatology, Department of Internal Medicine III, Medical University of Vienna, Vienna, Austria.
  • Kuess P; Department of Radiation Oncology, Division of Medical Radiation Physics, Medical University of Vienna, Vienna, Austria.
  • Sexl V; Institute of Pharmacology and Toxicology, Department for Biomedical Sciences, University of Veterinary Medicine Vienna, Vienna, Austria.
  • Müller M; Biomodels Austria and Institute of Animal Breeding and Genetics, University of Veterinary Medicine, Vienna, Austria.
  • Mikula M; Center of Pathobiochemistry and Genetics, Institute of Medical Genetics, Medical University of Vienna, Vienna, Austria.
  • Weckwerth W; Department of Ecogenomics and Systems Biology and Vienna Metabolomics Center (VIME), University of Vienna, Vienna, Austria.
  • Haschemi A; Department of Laboratory Medicine (KILM), Medical University of Vienna, Vienna, Austria.
  • Susani M; Clinical Institute of Pathology, Medical University of Vienna, Vienna, Austria.
  • Hengstschläger M; Center of Pathobiochemistry and Genetics, Institute of Medical Genetics, Medical University of Vienna, Vienna, Austria.
  • Gambello MJ; Department of Human Genetics, Emory University, Atlanta, Georgia, USA.
  • Weichhart T; Center of Pathobiochemistry and Genetics, Institute of Medical Genetics, Medical University of Vienna, Vienna, Austria.
Nat Immunol ; 18(3): 293-302, 2017 03.
Article em En | MEDLINE | ID: mdl-28092373
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Sarcoidose / Proteínas Supressoras de Tumor / Complexos Multiproteicos / Serina-Treonina Quinases TOR / Granuloma / Macrófagos Limite: Animals / Humans Idioma: En Ano de publicação: 2017 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Sarcoidose / Proteínas Supressoras de Tumor / Complexos Multiproteicos / Serina-Treonina Quinases TOR / Granuloma / Macrófagos Limite: Animals / Humans Idioma: En Ano de publicação: 2017 Tipo de documento: Article