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Molecular Mechanism of Disease-Associated Mutations in the Pre-M1 Helix of NMDA Receptors and Potential Rescue Pharmacology.
Ogden, Kevin K; Chen, Wenjuan; Swanger, Sharon A; McDaniel, Miranda J; Fan, Linlin Z; Hu, Chun; Tankovic, Anel; Kusumoto, Hirofumi; Kosobucki, Gabrielle J; Schulien, Anthony J; Su, Zhuocheng; Pecha, Joseph; Bhattacharya, Subhrajit; Petrovski, Slavé; Cohen, Adam E; Aizenman, Elias; Traynelis, Stephen F; Yuan, Hongjie.
Afiliação
  • Ogden KK; Department of Pharmacology, Emory University School of Medicine, Atlanta, Georgia, United States of America.
  • Chen W; Department of Pharmacology, Emory University School of Medicine, Atlanta, Georgia, United States of America.
  • Swanger SA; Department of Neurology, Xiangya Hospital, Central South University, Changsha, China.
  • McDaniel MJ; Department of Pharmacology, Emory University School of Medicine, Atlanta, Georgia, United States of America.
  • Fan LZ; Department of Pharmacology, Emory University School of Medicine, Atlanta, Georgia, United States of America.
  • Hu C; Department of Chemistry and Chemical Biology, Howard Hughes Medical Institute, Harvard University, Cambridge, Massachusetts, United States of America.
  • Tankovic A; Department of Pharmacology, Emory University School of Medicine, Atlanta, Georgia, United States of America.
  • Kusumoto H; Department of Pharmacology, Emory University School of Medicine, Atlanta, Georgia, United States of America.
  • Kosobucki GJ; Department of Pharmacology, Emory University School of Medicine, Atlanta, Georgia, United States of America.
  • Schulien AJ; Department of Neurobiology, University of Pittsburgh School of Medicine and Pittsburgh Institute for Neurodegenerative Diseases, Pittsburgh, Pennsylvania, United States of America.
  • Su Z; Department of Neurobiology, University of Pittsburgh School of Medicine and Pittsburgh Institute for Neurodegenerative Diseases, Pittsburgh, Pennsylvania, United States of America.
  • Pecha J; Department of Pharmacology, Emory University School of Medicine, Atlanta, Georgia, United States of America.
  • Bhattacharya S; Department of Pharmacology, Emory University School of Medicine, Atlanta, Georgia, United States of America.
  • Petrovski S; Department of Pharmacology, Emory University School of Medicine, Atlanta, Georgia, United States of America.
  • Cohen AE; Department of Medicine, The University of Melbourne, Austin Health and Royal Melbourne Hospital, Melbourne, Victoria, Australia.
  • Aizenman E; Department of Chemistry and Chemical Biology, Howard Hughes Medical Institute, Harvard University, Cambridge, Massachusetts, United States of America.
  • Traynelis SF; Department of Neurobiology, University of Pittsburgh School of Medicine and Pittsburgh Institute for Neurodegenerative Diseases, Pittsburgh, Pennsylvania, United States of America.
  • Yuan H; Department of Pharmacology, Emory University School of Medicine, Atlanta, Georgia, United States of America.
PLoS Genet ; 13(1): e1006536, 2017 Jan.
Article em En | MEDLINE | ID: mdl-28095420

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Ativação do Canal Iônico / Receptores de N-Metil-D-Aspartato / Mutação de Sentido Incorreto / Proteínas do Tecido Nervoso / Doenças do Sistema Nervoso Tipo de estudo: Guideline / Risk_factors_studies Limite: Animals / Humans Idioma: En Ano de publicação: 2017 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Ativação do Canal Iônico / Receptores de N-Metil-D-Aspartato / Mutação de Sentido Incorreto / Proteínas do Tecido Nervoso / Doenças do Sistema Nervoso Tipo de estudo: Guideline / Risk_factors_studies Limite: Animals / Humans Idioma: En Ano de publicação: 2017 Tipo de documento: Article