miR-345 inhibits tumor metastasis and EMT by targeting IRF1-mediated mTOR/STAT3/AKT pathway in hepatocellular carcinoma.

Yu, Miao; Xue, Huanzhou; Wang, Yadong; Shen, Quan; Jiang, Qingfeng; Zhang, Xiao; Li, Ke; Jia, Meng; Jia, Jiangkun; Xu, Jian; Tian, Yuwei

Yu, Miao; Xue, Huanzhou; Wang, Yadong; Shen, Quan; Jiang, Qingfeng; Zhang, Xiao; Li, Ke; Jia, Meng; Jia, Jiangkun; Xu, Jian; Tian, Yuwei.

Afiliação

Yu M; Department of Hepatobiliary Surgery, People's Hospital of Zhengzhou University, Zhengzhou, Henan 450003, P.R. China.
Xue H; Department of Hepatobiliary Surgery, People's Hospital of Zhengzhou University, Zhengzhou, Henan 450003, P.R. China.
Wang Y; Department of Hepatobiliary Surgery, People's Hospital of Zhengzhou University, Zhengzhou, Henan 450003, P.R. China.
Shen Q; Department of Hepatobiliary Surgery, People's Hospital of Zhengzhou University, Zhengzhou, Henan 450003, P.R. China.
Jiang Q; Department of Hepatobiliary Surgery, People's Hospital of Zhengzhou University, Zhengzhou, Henan 450003, P.R. China.
Zhang X; Department of Hepatobiliary Surgery, People's Hospital of Zhengzhou University, Zhengzhou, Henan 450003, P.R. China.
Li K; Department of Hepatobiliary Surgery, People's Hospital of Zhengzhou University, Zhengzhou, Henan 450003, P.R. China.
Jia M; Department of Hepatobiliary Surgery, People's Hospital of Zhengzhou University, Zhengzhou, Henan 450003, P.R. China.
Jia J; Department of Hepatobiliary Surgery, People's Hospital of Zhengzhou University, Zhengzhou, Henan 450003, P.R. China.
Xu J; Department of Hepatobiliary Surgery, People's Hospital of Zhengzhou University, Zhengzhou, Henan 450003, P.R. China.
Tian Y; Department of Hepatobiliary Surgery, People's Hospital of Zhengzhou University, Zhengzhou, Henan 450003, P.R. China.

Int J Oncol ; 50(3): 975-983, 2017 Mar.

Article em En | MEDLINE | ID: mdl-28098858

Assuntos

Carcinoma Hepatocelular/patologia; Transição Epitelial-Mesenquimal/genética; Fator Regulador 1 de Interferon/metabolismo; Neoplasias Hepáticas/patologia; MicroRNAs/genética; Carcinoma Hepatocelular/genética; Linhagem Celular Tumoral; Movimento Celular/genética; Proliferação de Células/genética; Feminino; Células Hep G2; Humanos; Fator Regulador 1 de Interferon/antagonistas & inibidores; Fator Regulador 1 de Interferon/genética; Neoplasias Hepáticas/genética; Masculino; Pessoa de Meia-Idade; Metástase Neoplásica/genética; Proteínas Proto-Oncogênicas c-akt/metabolismo; RNA Mensageiro/biossíntese; Fator de Transcrição STAT3/metabolismo; Fatores de Transcrição da Família Snail/metabolismo; Serina-Treonina Quinases TOR/metabolismo

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Carcinoma Hepatocelular / MicroRNAs / Fator Regulador 1 de Interferon / Transição Epitelial-Mesenquimal / Neoplasias Hepáticas Tipo de estudo: Prognostic_studies Limite: Female / Humans / Male / Middle aged Idioma: En Ano de publicação: 2017 Tipo de documento: Article

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