Fluorogenic probes to monitor cytosolic phospholipase A2 activity.
Chem Commun (Camb)
; 53(11): 1813-1816, 2017 Feb 02.
Article
em En
| MEDLINE
| ID: mdl-28106899
ABSTRACT
Arachidonic acid derivatives equipped with either one or two fluorescent groups attached to the tip of the alkyl chains were synthesized and shown to function as inhibitor and substrate probes of cPLA2. The inhibitor probe was demonstrated to perform dual functions of inhibition and imaging while the substrate probe could be used for activity assay.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Citosol
/
Fosfolipases A2
/
Corantes Fluorescentes
Limite:
Humans
Idioma:
En
Ano de publicação:
2017
Tipo de documento:
Article