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Chiral resolution of serial potent and selective σ1 ligands and biological evaluation of (-)-[18F]TZ3108 in rodent and the nonhuman primate brain.
Yue, Xuyi; Jin, Hongjun; Luo, Zonghua; Liu, Hui; Zhang, Xiang; McSpadden, Ethan D; Tian, Linlin; Flores, Hubert P; Perlmutter, Joel S; Parsons, Stanley M; Tu, Zhude.
Afiliação
  • Yue X; Mallinckrodt Institute of Radiology, Washington University School of Medicine, St Louis, MO, United States.
  • Jin H; Mallinckrodt Institute of Radiology, Washington University School of Medicine, St Louis, MO, United States.
  • Luo Z; Mallinckrodt Institute of Radiology, Washington University School of Medicine, St Louis, MO, United States.
  • Liu H; Mallinckrodt Institute of Radiology, Washington University School of Medicine, St Louis, MO, United States.
  • Zhang X; Mallinckrodt Institute of Radiology, Washington University School of Medicine, St Louis, MO, United States.
  • McSpadden ED; Department of Chemistry and Biochemistry, University of California, Santa Barbara, CA, United States.
  • Tian L; Department of Neurology, Washington University School of Medicine, St Louis, MO, United States.
  • Flores HP; Department of Neurology, Washington University School of Medicine, St Louis, MO, United States.
  • Perlmutter JS; Mallinckrodt Institute of Radiology, Washington University School of Medicine, St Louis, MO, United States; Department of Neurology, Washington University School of Medicine, St Louis, MO, United States.
  • Parsons SM; Department of Chemistry and Biochemistry, University of California, Santa Barbara, CA, United States.
  • Tu Z; Mallinckrodt Institute of Radiology, Washington University School of Medicine, St Louis, MO, United States. Electronic address: tuz@mir.wustl.edu.
Bioorg Med Chem ; 25(4): 1533-1542, 2017 02 15.
Article em En | MEDLINE | ID: mdl-28129990
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Encéfalo / Receptores sigma / Compostos Radiofarmacêuticos Limite: Animals Idioma: En Ano de publicação: 2017 Tipo de documento: Article
Texto completo
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PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Encéfalo / Receptores sigma / Compostos Radiofarmacêuticos Limite: Animals Idioma: En Ano de publicação: 2017 Tipo de documento: Article