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Translational Pharmacology of the Metabotropic Glutamate 2 Receptor-Preferring Agonist LY2812223 in the Animal and Human Brain.
Felder, Christian C; Schober, Douglas A; Tu, Yuan; Quets, Anne; Xiao, Hongling; Watt, Marla; Siuda, Ed; Nisenbaum, Eric; Xiang, Chuanxi; Heinz, Beverly; Prieto, Lourdes; McKinzie, David L; Monn, James A.
Afiliação
  • Felder CC; Lilly Research Laboratories, Eli Lilly and Company, Indianapolis, Indiana (C.C.F., D.A.S., Y.T., A.Q., H.X., M.W., E.S., E.N., C.X., B.H., D.L.M., J.A.M.); and Lilly Research Laboratories, Eli Lilly and Company, Alcobendas, Spain (L.P.) felder_christian@lilly.com.
  • Schober DA; Lilly Research Laboratories, Eli Lilly and Company, Indianapolis, Indiana (C.C.F., D.A.S., Y.T., A.Q., H.X., M.W., E.S., E.N., C.X., B.H., D.L.M., J.A.M.); and Lilly Research Laboratories, Eli Lilly and Company, Alcobendas, Spain (L.P.).
  • Tu Y; Lilly Research Laboratories, Eli Lilly and Company, Indianapolis, Indiana (C.C.F., D.A.S., Y.T., A.Q., H.X., M.W., E.S., E.N., C.X., B.H., D.L.M., J.A.M.); and Lilly Research Laboratories, Eli Lilly and Company, Alcobendas, Spain (L.P.).
  • Quets A; Lilly Research Laboratories, Eli Lilly and Company, Indianapolis, Indiana (C.C.F., D.A.S., Y.T., A.Q., H.X., M.W., E.S., E.N., C.X., B.H., D.L.M., J.A.M.); and Lilly Research Laboratories, Eli Lilly and Company, Alcobendas, Spain (L.P.).
  • Xiao H; Lilly Research Laboratories, Eli Lilly and Company, Indianapolis, Indiana (C.C.F., D.A.S., Y.T., A.Q., H.X., M.W., E.S., E.N., C.X., B.H., D.L.M., J.A.M.); and Lilly Research Laboratories, Eli Lilly and Company, Alcobendas, Spain (L.P.).
  • Watt M; Lilly Research Laboratories, Eli Lilly and Company, Indianapolis, Indiana (C.C.F., D.A.S., Y.T., A.Q., H.X., M.W., E.S., E.N., C.X., B.H., D.L.M., J.A.M.); and Lilly Research Laboratories, Eli Lilly and Company, Alcobendas, Spain (L.P.).
  • Siuda E; Lilly Research Laboratories, Eli Lilly and Company, Indianapolis, Indiana (C.C.F., D.A.S., Y.T., A.Q., H.X., M.W., E.S., E.N., C.X., B.H., D.L.M., J.A.M.); and Lilly Research Laboratories, Eli Lilly and Company, Alcobendas, Spain (L.P.).
  • Nisenbaum E; Lilly Research Laboratories, Eli Lilly and Company, Indianapolis, Indiana (C.C.F., D.A.S., Y.T., A.Q., H.X., M.W., E.S., E.N., C.X., B.H., D.L.M., J.A.M.); and Lilly Research Laboratories, Eli Lilly and Company, Alcobendas, Spain (L.P.).
  • Xiang C; Lilly Research Laboratories, Eli Lilly and Company, Indianapolis, Indiana (C.C.F., D.A.S., Y.T., A.Q., H.X., M.W., E.S., E.N., C.X., B.H., D.L.M., J.A.M.); and Lilly Research Laboratories, Eli Lilly and Company, Alcobendas, Spain (L.P.).
  • Heinz B; Lilly Research Laboratories, Eli Lilly and Company, Indianapolis, Indiana (C.C.F., D.A.S., Y.T., A.Q., H.X., M.W., E.S., E.N., C.X., B.H., D.L.M., J.A.M.); and Lilly Research Laboratories, Eli Lilly and Company, Alcobendas, Spain (L.P.).
  • Prieto L; Lilly Research Laboratories, Eli Lilly and Company, Indianapolis, Indiana (C.C.F., D.A.S., Y.T., A.Q., H.X., M.W., E.S., E.N., C.X., B.H., D.L.M., J.A.M.); and Lilly Research Laboratories, Eli Lilly and Company, Alcobendas, Spain (L.P.).
  • McKinzie DL; Lilly Research Laboratories, Eli Lilly and Company, Indianapolis, Indiana (C.C.F., D.A.S., Y.T., A.Q., H.X., M.W., E.S., E.N., C.X., B.H., D.L.M., J.A.M.); and Lilly Research Laboratories, Eli Lilly and Company, Alcobendas, Spain (L.P.).
  • Monn JA; Lilly Research Laboratories, Eli Lilly and Company, Indianapolis, Indiana (C.C.F., D.A.S., Y.T., A.Q., H.X., M.W., E.S., E.N., C.X., B.H., D.L.M., J.A.M.); and Lilly Research Laboratories, Eli Lilly and Company, Alcobendas, Spain (L.P.).
J Pharmacol Exp Ther ; 361(1): 190-197, 2017 04.
Article em En | MEDLINE | ID: mdl-28138041
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Triazóis / Compostos Bicíclicos com Pontes / Encéfalo / Receptores de Glutamato Metabotrópico / Agonistas de Aminoácidos Excitatórios / Agonismo Parcial de Drogas Limite: Animals / Humans Idioma: En Ano de publicação: 2017 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Triazóis / Compostos Bicíclicos com Pontes / Encéfalo / Receptores de Glutamato Metabotrópico / Agonistas de Aminoácidos Excitatórios / Agonismo Parcial de Drogas Limite: Animals / Humans Idioma: En Ano de publicação: 2017 Tipo de documento: Article