Human olfactory mesenchymal stromal cell transplants promote remyelination and earlier improvement in gait co-ordination after spinal cord injury.

Lindsay, Susan L; Toft, Andrew; Griffin, Jacob; M M Emraja, Ahmed; Barnett, Susan Carol; Riddell, John S

Lindsay, Susan L; Toft, Andrew; Griffin, Jacob; M M Emraja, Ahmed; Barnett, Susan Carol; Riddell, John S.

Afiliação

Lindsay SL; Institute of Infection, College of Medical Veterinary and Life Sciences, Inflammation, and Immunity, University of Glasgow, Glasgow, G12 8TA, United Kingdom.
Toft A; Institute of Neuroscience and Psychology, College of Medical Veterinary and Life Sciences, West Medical Building, University of Glasgow, G12 8QQ, United Kingdom.
Griffin J; Institute of Neuroscience and Psychology, College of Medical Veterinary and Life Sciences, West Medical Building, University of Glasgow, G12 8QQ, United Kingdom.
M M Emraja A; Institute of Neuroscience and Psychology, College of Medical Veterinary and Life Sciences, West Medical Building, University of Glasgow, G12 8QQ, United Kingdom.
Barnett SC; Institute of Infection, College of Medical Veterinary and Life Sciences, Inflammation, and Immunity, University of Glasgow, Glasgow, G12 8TA, United Kingdom.
Riddell JS; Institute of Neuroscience and Psychology, College of Medical Veterinary and Life Sciences, West Medical Building, University of Glasgow, G12 8QQ, United Kingdom.

Glia ; 65(4): 639-656, 2017 04.

Article em En | MEDLINE | ID: mdl-28144983

Assuntos

Transtornos Neurológicos da Marcha/etiologia; Transtornos Neurológicos da Marcha/cirurgia; Transplante de Células-Tronco Mesenquimais/métodos; Mucosa Olfatória/citologia; Remielinização/fisiologia; Traumatismos da Medula Espinal/complicações; Animais; Moléculas de Adesão Celular Neuronais/metabolismo; Modelos Animais de Doenças; Eletroencefalografia; Potenciais Somatossensoriais Evocados/fisiologia; Comportamento Exploratório/fisiologia; Humanos; Locomoção/fisiologia; Masculino; Proteína P0 da Mielina/metabolismo; Proteínas do Tecido Nervoso/metabolismo; Medição da Dor; Ratos; Ratos Sprague-Dawley; Suporte de Carga

Palavras-chave

gait analysis; mesenchymal stromal cells; remyelination; spinal cord injury; transplant

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Traumatismos da Medula Espinal / Mucosa Olfatória / Transtornos Neurológicos da Marcha / Transplante de Células-Tronco Mesenquimais / Remielinização Limite: Animals / Humans / Male Idioma: En Ano de publicação: 2017 Tipo de documento: Article

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