Simple in vitro generation of human leukocyte antigen-G-expressing T-regulatory cells through pharmacological hypomethylation for adoptive cellular immunotherapy against graft-versus-host disease.

Stamou, Panagiota; Marioli, Dimitra; Patmanidi, Alexandra L; Sgourou, Argyro; Vittoraki, Angeliki; Theofani, Efthymia; Pierides, Chryso; Taraviras, Stavros; Costeas, Paul A; Spyridonidis, Alexandros

Stamou, Panagiota; Marioli, Dimitra; Patmanidi, Alexandra L; Sgourou, Argyro; Vittoraki, Angeliki; Theofani, Efthymia; Pierides, Chryso; Taraviras, Stavros; Costeas, Paul A; Spyridonidis, Alexandros.

Afiliação

Stamou P; Bone Marrow Transplantation Unit, Medical School, University of Patras, Patras, Greece.
Marioli D; Bone Marrow Transplantation Unit, Medical School, University of Patras, Patras, Greece.
Patmanidi AL; Department of Physiology, Medical School, University of Patras, Patras, Greece.
Sgourou A; Biology Lab, School of Science and Technology, Hellenic Open University, Patras, Greece.
Vittoraki A; Bone Marrow Transplantation Unit, Medical School, University of Patras, Patras, Greece.
Theofani E; Bone Marrow Transplantation Unit, Medical School, University of Patras, Patras, Greece.
Pierides C; Molecular Haematology and Immunogenetics Center, Karaiskakio Foundation, Nicosia, Cyprus.
Taraviras S; Department of Physiology, Medical School, University of Patras, Patras, Greece.
Costeas PA; Molecular Haematology and Immunogenetics Center, Karaiskakio Foundation, Nicosia, Cyprus.
Spyridonidis A; Bone Marrow Transplantation Unit, Medical School, University of Patras, Patras, Greece. Electronic address: spyridonidis@upatras.gr.

Cytotherapy ; 19(4): 521-530, 2017 04.

Article em En | MEDLINE | ID: mdl-28162915

Assuntos

Engenharia Celular/métodos; Doença Enxerto-Hospedeiro/terapia; Antígenos HLA-G/metabolismo; Imunoterapia Adotiva/métodos; Linfócitos T Reguladores/metabolismo; Linfócitos T Reguladores/transplante; Azacitidina/análogos & derivados; Azacitidina/farmacologia; Técnicas de Cultura de Células; Células Cultivadas; Metilação de DNA/efeitos dos fármacos; Decitabina; Regulação da Expressão Gênica/efeitos dos fármacos; Doença Enxerto-Hospedeiro/imunologia; Antígenos HLA-G/genética; Humanos; Linfócitos T Reguladores/citologia; Linfócitos T Reguladores/imunologia

Palavras-chave

adoptive cell therapy; graft-versus-host disease; human leukocyte antigen-G; hypomethylation; regulatory T cells

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Imunoterapia Adotiva / Linfócitos T Reguladores / Antígenos HLA-G / Engenharia Celular / Doença Enxerto-Hospedeiro Limite: Humans Idioma: En Ano de publicação: 2017 Tipo de documento: Article

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google