Synthesis, Anticonvulsant Activity, and SAR Study of Novel 4-Quinazolinone Derivatives.

Noureldin, Nada A; Kothayer, Hend; Lashine, El-Sayed M; Baraka, Mohamed M; El-Eraky, Wafaa; Awdan, Sally A El

Noureldin, Nada A; Kothayer, Hend; Lashine, El-Sayed M; Baraka, Mohamed M; El-Eraky, Wafaa; Awdan, Sally A El.

Afiliação

Noureldin NA; Faculty of Pharmacy, Department of Medicinal Chemistry, Zagazig University, Zagazig, Egypt.
Kothayer H; Faculty of Pharmacy, Department of Medicinal Chemistry, Zagazig University, Zagazig, Egypt.
Lashine EM; Faculty of Pharmacy, Department of Medicinal Chemistry, Zagazig University, Zagazig, Egypt.
Baraka MM; Faculty of Pharmacy, Department of Medicinal Chemistry, Zagazig University, Zagazig, Egypt.
El-Eraky W; Department of Pharmacology, National Research Center, Dokki, Cairo, Egypt.
Awdan SA; Department of Pharmacology, National Research Center, Dokki, Cairo, Egypt.

Arch Pharm (Weinheim) ; 350(2)2017 Feb.

Article em En | MEDLINE | ID: mdl-28177550

Assuntos

Anticonvulsivantes/síntese química; Anticonvulsivantes/farmacologia; Quinazolinonas/síntese química; Quinazolinonas/farmacologia; Convulsões/prevenção & controle; Animais; Relação Dose-Resposta a Droga; Eletrochoque; Camundongos; Pentilenotetrazol; Teste de Desempenho do Rota-Rod; Relação Estrutura-Atividade

Palavras-chave

Amino acids; Anticonvulsant; Quinazolin-4(3H)-ones

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Convulsões / Quinazolinonas / Anticonvulsivantes Limite: Animals Idioma: En Ano de publicação: 2017 Tipo de documento: Article

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