Tris (1,3-dichloro-2-propyl) phosphate induces toxicity by stimulating CaMK2 in PC12 cells.

Li, Chaonan; Li, Li; Lin, Bencheng; Fang, Yanjun; Yang, Honglian; Liu, Huanliang; Xi, Zhuge

Li, Chaonan; Li, Li; Lin, Bencheng; Fang, Yanjun; Yang, Honglian; Liu, Huanliang; Xi, Zhuge.

Afiliação

Li C; Department of Toxicology, A Key Laboratory of Risk Assessment and Control for Environment and Food Safety, Tianjin Institute of Health and Environmental Medicine, Tianjin, China.
Li L; Department of Chronic Disease Prevention and Treatment, Mentougou Center for Disease Prevention and Control, Beijing, China.
Lin B; Department of Toxicology, A Key Laboratory of Risk Assessment and Control for Environment and Food Safety, Tianjin Institute of Health and Environmental Medicine, Tianjin, China.
Fang Y; Department of Toxicology, A Key Laboratory of Risk Assessment and Control for Environment and Food Safety, Tianjin Institute of Health and Environmental Medicine, Tianjin, China.
Yang H; Department of Toxicology, A Key Laboratory of Risk Assessment and Control for Environment and Food Safety, Tianjin Institute of Health and Environmental Medicine, Tianjin, China.
Liu H; Department of Toxicology, A Key Laboratory of Risk Assessment and Control for Environment and Food Safety, Tianjin Institute of Health and Environmental Medicine, Tianjin, China.
Xi Z; Department of Toxicology, A Key Laboratory of Risk Assessment and Control for Environment and Food Safety, Tianjin Institute of Health and Environmental Medicine, Tianjin, China.

Environ Toxicol ; 32(6): 1784-1791, 2017 Jun.

Article em En | MEDLINE | ID: mdl-28181390

Assuntos

Proteína Quinase Tipo 2 Dependente de Cálcio-Calmodulina/metabolismo; Retardadores de Chama/toxicidade; Sistema de Sinalização das MAP Quinases/efeitos dos fármacos; Compostos Organofosforados/toxicidade; Animais; Sobrevivência Celular/efeitos dos fármacos; Ativação Enzimática/efeitos dos fármacos; Proteínas Quinases JNK Ativadas por Mitógeno/metabolismo; Proteína Quinase 3 Ativada por Mitógeno/metabolismo; Proteínas Quinases Ativadas por Mitógeno/metabolismo; Células PC12; Fosforilação; Proteínas Serina-Treonina Quinases/metabolismo; Ratos; Proteínas Quinases p38 Ativadas por Mitógeno/metabolismo

Palavras-chave

calmodulin dependent protein kinase; intracellular calcium ions; mitogen-activated protein kinases; toxicity; tris (1,3-dichloro-2-propyl) phosphate

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Compostos Organofosforados / Sistema de Sinalização das MAP Quinases / Proteína Quinase Tipo 2 Dependente de Cálcio-Calmodulina / Retardadores de Chama Limite: Animals Idioma: En Ano de publicação: 2017 Tipo de documento: Article

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google