Integrated genomic analyses of de novo pathways underlying atypical meningiomas.

Harmanci, Akdes Serin; Youngblood, Mark W; Clark, Victoria E; Coskun, Süleyman; Henegariu, Octavian; Duran, Daniel; Erson-Omay, E Zeynep; Kaulen, Leon D; Lee, Tong Ihn; Abraham, Brian J; Simon, Matthias; Krischek, Boris; Timmer, Marco; Goldbrunner, Roland; Omay, S Bülent; Baranoski, Jacob; Baran, Burçin; Carrión-Grant, Geneive; Bai, Hanwen; Mishra-Gorur, Ketu; Schramm, Johannes; Moliterno, Jennifer; Vortmeyer, Alexander O; Bilgüvar, Kaya; Yasuno, Katsuhito; Young, Richard A; Günel, Murat

Harmanci, Akdes Serin; Youngblood, Mark W; Clark, Victoria E; Coskun, Süleyman; Henegariu, Octavian; Duran, Daniel; Erson-Omay, E Zeynep; Kaulen, Leon D; Lee, Tong Ihn; Abraham, Brian J; Simon, Matthias; Krischek, Boris; Timmer, Marco; Goldbrunner, Roland; Omay, S Bülent; Baranoski, Jacob; Baran, Burçin; Carrión-Grant, Geneive; Bai, Hanwen; Mishra-Gorur, Ketu; Schramm, Johannes; Moliterno, Jennifer; Vortmeyer, Alexander O; Bilgüvar, Kaya; Yasuno, Katsuhito; Young, Richard A; Günel, Murat.

Afiliação

Harmanci AS; Yale Program in Brain Tumor Research, Yale School of Medicine, New Haven, Connecticut 06510, USA.
Youngblood MW; Department of Neurosurgery, Yale School of Medicine, New Haven, Connecticut 06510, USA.
Clark VE; Yale Program in Brain Tumor Research, Yale School of Medicine, New Haven, Connecticut 06510, USA.
Coskun S; Department of Neurosurgery, Yale School of Medicine, New Haven, Connecticut 06510, USA.
Henegariu O; Department of Genetics, Yale School of Medicine, New Haven, Connecticut 06510, USA.
Duran D; Yale Program in Brain Tumor Research, Yale School of Medicine, New Haven, Connecticut 06510, USA.
Erson-Omay EZ; Department of Neurosurgery, Yale School of Medicine, New Haven, Connecticut 06510, USA.
Kaulen LD; Department of Genetics, Yale School of Medicine, New Haven, Connecticut 06510, USA.
Lee TI; Yale Program in Brain Tumor Research, Yale School of Medicine, New Haven, Connecticut 06510, USA.
Abraham BJ; Department of Neurosurgery, Yale School of Medicine, New Haven, Connecticut 06510, USA.
Simon M; Yale Program in Brain Tumor Research, Yale School of Medicine, New Haven, Connecticut 06510, USA.
Krischek B; Department of Neurosurgery, Yale School of Medicine, New Haven, Connecticut 06510, USA.
Timmer M; Department of Genetics, Yale School of Medicine, New Haven, Connecticut 06510, USA.
Goldbrunner R; Department of Neurobiology, Yale School of Medicine, New Haven, Connecticut 06510, USA.
Omay SB; Yale Program on Neurogenetics, Yale School of Medicine, New Haven, Connecticut 06510, USA.
Baranoski J; Yale Program in Brain Tumor Research, Yale School of Medicine, New Haven, Connecticut 06510, USA.
Baran B; Department of Neurosurgery, Yale School of Medicine, New Haven, Connecticut 06510, USA.
Carrión-Grant G; Yale Program in Brain Tumor Research, Yale School of Medicine, New Haven, Connecticut 06510, USA.
Bai H; Department of Neurosurgery, Yale School of Medicine, New Haven, Connecticut 06510, USA.
Mishra-Gorur K; Yale Program in Brain Tumor Research, Yale School of Medicine, New Haven, Connecticut 06510, USA.
Schramm J; Department of Neurosurgery, Yale School of Medicine, New Haven, Connecticut 06510, USA.
Moliterno J; Whitehead Institute for Biomedical Research, 9 Cambridge Center, Cambridge, Massachusetts 02142, USA.
Vortmeyer AO; Whitehead Institute for Biomedical Research, 9 Cambridge Center, Cambridge, Massachusetts 02142, USA.
Bilgüvar K; Department of Neurosurgery, University of Bonn Medical School, Bonn 53105, Germany.
Yasuno K; Department of General Neurosurgery, University Hospital of Cologne, Cologne 50937, Germany.
Young RA; Department of General Neurosurgery, University Hospital of Cologne, Cologne 50937, Germany.
Günel M; Department of General Neurosurgery, University Hospital of Cologne, Cologne 50937, Germany.

Nat Commun ; 8: 14433, 2017 02 14.

Article em En | MEDLINE | ID: mdl-28195122

Assuntos

Redes Reguladoras de Genes/genética; Redes Reguladoras de Genes/fisiologia; Genoma; Genômica/métodos; Neoplasias Meníngeas/genética; Neoplasias Meníngeas/metabolismo; Meningioma/genética; Meningioma/metabolismo; Sítios de Ligação; Neoplasias Encefálicas/genética; Neoplasias Encefálicas/metabolismo; Transformação Celular Neoplásica/genética; Instabilidade Cromossômica; Análise por Conglomerados; Metilação de DNA; Fator de Transcrição E2F2/metabolismo; Proteína Potenciadora do Homólogo 2 de Zeste/metabolismo; Epigenômica/métodos; Exoma/genética; Proteína Forkhead Box M1/metabolismo; Perfilação da Expressão Gênica; Regulação Neoplásica da Expressão Gênica; Inativação Gênica; Genes da Neurofibromatose 2; Técnicas de Genotipagem; Células-Tronco Embrionárias Humanas/metabolismo; Humanos; Histona Desmetilases com o Domínio Jumonji/genética; Técnicas de Sonda Molecular; Mutação; Fenótipo; Complexo Repressor Polycomb 2/genética; Complexo Repressor Polycomb 2/metabolismo; Regiões Promotoras Genéticas; RNA Mensageiro/metabolismo; Proteína SMARCB1/genética; Análise de Sequência; Transdução de Sinais/genética; Transcriptoma

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Genoma / Genômica / Redes Reguladoras de Genes / Neoplasias Meníngeas / Meningioma Idioma: En Ano de publicação: 2017 Tipo de documento: Article

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