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An epigenetic modifier induces production of (10'S)-verruculide B, an inhibitor of protein tyrosine phosphatases by Phoma sp. nov. LG0217, a fungal endophyte of Parkinsonia microphylla.
Gubiani, Juliana R; Wijeratne, E M Kithsiri; Shi, Taoda; Araujo, Angela R; Arnold, A Elizabeth; Chapman, Eli; Gunatilaka, A A Leslie.
Afiliação
  • Gubiani JR; Natural Products Center, School of Natural Resources and the Environment, College of Agriculture and Life Sciences, University of Arizona, 250 E. Valencia Road, Tucson, AZ 85706, United States; NuBBE - Núcleo de Bioensaios, Biossíntese e Ecofisiologia de Produtos Naturais, Departamento de Química Or
  • Wijeratne EM; Natural Products Center, School of Natural Resources and the Environment, College of Agriculture and Life Sciences, University of Arizona, 250 E. Valencia Road, Tucson, AZ 85706, United States.
  • Shi T; Department of Pharmacology and Toxicology, College of Pharmacy, University of Arizona, Tucson, AZ 85721, United States.
  • Araujo AR; NuBBE - Núcleo de Bioensaios, Biossíntese e Ecofisiologia de Produtos Naturais, Departamento de Química Orgânica, Instituto de Química, UNESP, Universidade Estadual Paulista, Araraquara, SP 14800-900, Brazil.
  • Arnold AE; School of Plant Sciences, College of Agriculture and Life Sciences, University of Arizona, Tucson, AZ 85721, United States.
  • Chapman E; Department of Pharmacology and Toxicology, College of Pharmacy, University of Arizona, Tucson, AZ 85721, United States.
  • Gunatilaka AA; Natural Products Center, School of Natural Resources and the Environment, College of Agriculture and Life Sciences, University of Arizona, 250 E. Valencia Road, Tucson, AZ 85706, United States. Electronic address: leslieg1@email.arizona.edu.
Bioorg Med Chem ; 25(6): 1860-1866, 2017 03 15.
Article em En | MEDLINE | ID: mdl-28202316
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Ascomicetos / Sesquiterpenos / Proteínas Tirosina Fosfatases / Epigênese Genética / Inibidores Enzimáticos / Fabaceae Idioma: En Ano de publicação: 2017 Tipo de documento: Article
Texto completo
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XML
PubMed Links
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Ascomicetos / Sesquiterpenos / Proteínas Tirosina Fosfatases / Epigênese Genética / Inibidores Enzimáticos / Fabaceae Idioma: En Ano de publicação: 2017 Tipo de documento: Article