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Heteroaryldihydropyrimidine (HAP) and Sulfamoylbenzamide (SBA) Inhibit Hepatitis B Virus Replication by Different Molecular Mechanisms.
Zhou, Zheng; Hu, Taishan; Zhou, Xue; Wildum, Steffen; Garcia-Alcalde, Fernando; Xu, Zhiheng; Wu, Daitze; Mao, Yi; Tian, Xiaojun; Zhou, Yuan; Shen, Fang; Zhang, Zhisen; Tang, Guozhi; Najera, Isabel; Yang, Guang; Shen, Hong C; Young, John A T; Qin, Ning.
Afiliação
  • Zhou Z; Roche Pharma Research and Early Development, Chemical Biology, Roche Innovation Center Shanghai, Shanghai, 201203, China.
  • Hu T; Roche Pharma Research and Early Development, Medicinal Chemistry, Roche Innovation Center Shanghai, Shanghai, 201203, China.
  • Zhou X; Roche Pharma Research and Early Development, Immunology, Inflammation and Infectious Diseases Discovery and Translational Area, Roche Innovation Center Shanghai, Shanghai, 201203, China.
  • Wildum S; Roche Pharma Research and Early Development, Immunology, Inflammation and Infectious Diseases Discovery and Translational Area, Roche Innovation Center Basel, CH-4070 Basel, Switzerland.
  • Garcia-Alcalde F; Roche Pharma Research and Early Development, Immunology, Inflammation and Infectious Diseases Discovery and Translational Area, Roche Innovation Center Basel, CH-4070 Basel, Switzerland.
  • Xu Z; Roche Pharma Research and Early Development, Chemical Biology, Roche Innovation Center Shanghai, Shanghai, 201203, China.
  • Wu D; Roche Pharma Research and Early Development, Immunology, Inflammation and Infectious Diseases Discovery and Translational Area, Roche Innovation Center Shanghai, Shanghai, 201203, China.
  • Mao Y; Roche Pharma Research and Early Development, Immunology, Inflammation and Infectious Diseases Discovery and Translational Area, Roche Innovation Center Shanghai, Shanghai, 201203, China.
  • Tian X; Roche Pharma Research and Early Development, Immunology, Inflammation and Infectious Diseases Discovery and Translational Area, Roche Innovation Center Shanghai, Shanghai, 201203, China.
  • Zhou Y; Roche Pharma Research and Early Development, Immunology, Inflammation and Infectious Diseases Discovery and Translational Area, Roche Innovation Center Shanghai, Shanghai, 201203, China.
  • Shen F; Roche Pharma Research and Early Development, Immunology, Inflammation and Infectious Diseases Discovery and Translational Area, Roche Innovation Center Shanghai, Shanghai, 201203, China.
  • Zhang Z; Roche Pharma Research and Early Development, Medicinal Chemistry, Roche Innovation Center Shanghai, Shanghai, 201203, China.
  • Tang G; Roche Pharma Research and Early Development, Medicinal Chemistry, Roche Innovation Center Shanghai, Shanghai, 201203, China.
  • Najera I; Roche Pharma Research and Early Development, Immunology, Inflammation and Infectious Diseases Discovery and Translational Area, Roche Innovation Center Basel, CH-4070 Basel, Switzerland.
  • Yang G; Roche Pharma Research and Early Development, Immunology, Inflammation and Infectious Diseases Discovery and Translational Area, Roche Innovation Center Shanghai, Shanghai, 201203, China.
  • Shen HC; Roche Pharma Research and Early Development, Medicinal Chemistry, Roche Innovation Center Shanghai, Shanghai, 201203, China.
  • Young JA; Roche Pharma Research and Early Development, Immunology, Inflammation and Infectious Diseases Discovery and Translational Area, Roche Innovation Center Basel, CH-4070 Basel, Switzerland.
  • Qin N; Roche Pharma Research and Early Development, Chemical Biology, Roche Innovation Center Shanghai, Shanghai, 201203, China.
Sci Rep ; 7: 42374, 2017 02 13.
Article em En | MEDLINE | ID: mdl-28205569
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Pirimidinas / Replicação Viral / Benzamidas / Vírus da Hepatite B Limite: Humans Idioma: En Ano de publicação: 2017 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Pirimidinas / Replicação Viral / Benzamidas / Vírus da Hepatite B Limite: Humans Idioma: En Ano de publicação: 2017 Tipo de documento: Article