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The cationic small molecule GW4869 is cytotoxic to high phosphatidylserine-expressing myeloma cells.
Vuckovic, Slavica; Vandyke, Kate; Rickards, David A; McCauley Winter, Padraig; Brown, Simon H J; Mitchell, Todd W; Liu, Jun; Lu, Jun; Askenase, Philip W; Yuriev, Elizabeth; Capuano, Ben; Ramsland, Paul A; Hill, Geoffrey R; Zannettino, Andrew C W; Hutchinson, Andrew T.
Afiliação
  • Vuckovic S; The Bone Marrow Transplantation Laboratory, QIMR Berghofer Medical Research Institute, Brisbane, Qld, Australia.
  • Vandyke K; School of Medicine, University of Queensland, Brisbane, Qld, Australia.
  • Rickards DA; Mater Research, Translational Research Institute, Brisbane, Qld, Australia.
  • McCauley Winter P; Faculty of Health and Medical Sciences, SA Pathology, The University of Adelaide, Adelaide, SA.
  • Brown SHJ; Cancer Theme, South Australian Health and Medical Research Institute, SA Pathology, Adelaide, SA, Australia.
  • Mitchell TW; School of Life Sciences, Centre for Health Technologies and the iThree Institute, University of Technology Sydney, Ultimo, NSW, Australia.
  • Liu J; School of Life Sciences, Centre for Health Technologies and the iThree Institute, University of Technology Sydney, Ultimo, NSW, Australia.
  • Lu J; School of Biology and Illawarra Health and Medical Research Institute, University of Wollongong, Wollongong, NSW, Australia.
  • Askenase PW; School of Biology and Illawarra Health and Medical Research Institute, University of Wollongong, Wollongong, NSW, Australia.
  • Yuriev E; Department of Genetics, Yale Stem Cell Center, Yale Cancer Center and Yale Center for RNA Science and Medicine, New Haven, CT, USA.
  • Capuano B; Department of Genetics, Yale Stem Cell Center, Yale Cancer Center and Yale Center for RNA Science and Medicine, New Haven, CT, USA.
  • Ramsland PA; Section of Allergy and Clinical Immunology, Department of Internal Medicine, Yale School of Medicine, New Haven, CT, USA.
  • Hill GR; Medicinal Chemistry, Monash Institute of Pharmaceutical Sciences, Monash University, Parkville, VIC, Australia.
  • Zannettino ACW; Medicinal Chemistry, Monash Institute of Pharmaceutical Sciences, Monash University, Parkville, VIC, Australia.
  • Hutchinson AT; School of Science, RMIT University, Bundoora, VIC, Australia.
Br J Haematol ; 177(3): 423-440, 2017 05.
Article em En | MEDLINE | ID: mdl-28211573

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Fosfatidilserinas / Compostos de Benzilideno / Compostos de Anilina / Mieloma Múltiplo / Antineoplásicos Limite: Animals / Humans Idioma: En Ano de publicação: 2017 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Fosfatidilserinas / Compostos de Benzilideno / Compostos de Anilina / Mieloma Múltiplo / Antineoplásicos Limite: Animals / Humans Idioma: En Ano de publicação: 2017 Tipo de documento: Article