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Efficacy and safety of sirukumab in patients with active rheumatoid arthritis refractory to anti-TNF therapy (SIRROUND-T): a randomised, double-blind, placebo-controlled, parallel-group, multinational, phase 3 study.
Aletaha, Daniel; Bingham, Clifton O; Tanaka, Yoshiya; Agarwal, Prasheen; Kurrasch, Regina; Tak, Paul P; Popik, Sharon.
Afiliação
  • Aletaha D; Division of Rheumatology, Department of Internal Medicine 3, Medical University of Vienna, Vienna, Austria.
  • Bingham CO; Division of Rheumatology, Johns Hopkins University, Baltimore, MD, USA.
  • Tanaka Y; Department of Internal Medicine, University of Occupational and Environmental Health, Kitakyushu, Japan.
  • Agarwal P; Janssen Research & Development, LLC, Spring House, PA, USA.
  • Kurrasch R; GlaxoSmithKline, Collegeville, PA, USA.
  • Tak PP; GlaxoSmithKline, Stevenage, Hertfordshire, UK. Electronic address: paul-peter.x.tak@gsk.com.
  • Popik S; Janssen Research & Development, LLC, Spring House, PA, USA.
Lancet ; 389(10075): 1206-1217, 2017 03 25.
Article em En | MEDLINE | ID: mdl-28215362

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Artrite Reumatoide / Fator de Necrose Tumoral alfa / Antirreumáticos / Anticorpos Monoclonais Tipo de estudo: Clinical_trials Limite: Adult / Aged / Aged80 / Female / Humans / Male / Middle aged Idioma: En Ano de publicação: 2017 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Artrite Reumatoide / Fator de Necrose Tumoral alfa / Antirreumáticos / Anticorpos Monoclonais Tipo de estudo: Clinical_trials Limite: Adult / Aged / Aged80 / Female / Humans / Male / Middle aged Idioma: En Ano de publicação: 2017 Tipo de documento: Article