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Leupeptazin, a highly modified tripeptide isolated from cultures of a Streptomyces sp. inhibits cathepsin K.
Kruglyak, Natasha; Williams, David E; Chen, Henry; Law, Simon; Kaleta, Jadwiga; Villanueva, Ivan; Davies, Julian E; Andersen, Raymond J; Brömme, Dieter.
Afiliação
  • Kruglyak N; Department of Biochemistry and Molecular Biology, University of British Columbia, 2350 Health Sciences Mall, Vancouver, British Columbia V6T 1Z3, Canada; Present address: Department of Biochemistry, University of Toronto, 101 College St, TMDT 5-401, Toronto, Ontario M5G 1L7, Canada. Electronic addre
  • Williams DE; Departments of Chemistry and Earth, Ocean & Atmospheric Sciences, University of British Columbia, 2207 Main Mall, Vancouver, British Columbia V6T 1Z4, Canada.
  • Chen H; Department of Biochemistry and Molecular Biology, University of British Columbia, 2350 Health Sciences Mall, Vancouver, British Columbia V6T 1Z3, Canada.
  • Law S; Department of Biochemistry and Molecular Biology, University of British Columbia, 2350 Health Sciences Mall, Vancouver, British Columbia V6T 1Z3, Canada.
  • Kaleta J; Department of Oral, Biological and Medical Sciences, University of British Columbia, 2151 Westbrook Mall, Vancouver, British Columbia V6T 1Z3, Canada.
  • Villanueva I; Department of Microbiology and Immunology, University of British Columbia, 2350 Health Sciences Mall, Vancouver, British Columbia V6T 1Z3, Canada.
  • Davies JE; Department of Microbiology and Immunology, University of British Columbia, 2350 Health Sciences Mall, Vancouver, British Columbia V6T 1Z3, Canada.
  • Andersen RJ; Departments of Chemistry and Earth, Ocean & Atmospheric Sciences, University of British Columbia, 2207 Main Mall, Vancouver, British Columbia V6T 1Z4, Canada.
  • Brömme D; Department of Biochemistry and Molecular Biology, University of British Columbia, 2350 Health Sciences Mall, Vancouver, British Columbia V6T 1Z3, Canada; Department of Oral, Biological and Medical Sciences, University of British Columbia, 2151 Westbrook Mall, Vancouver, British Columbia V6T 1Z3, Can
Bioorg Med Chem Lett ; 27(6): 1397-1400, 2017 03 15.
Article em En | MEDLINE | ID: mdl-28228366
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Oligopeptídeos / Streptomyces / Catepsina K Limite: Humans Idioma: En Ano de publicação: 2017 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Oligopeptídeos / Streptomyces / Catepsina K Limite: Humans Idioma: En Ano de publicação: 2017 Tipo de documento: Article