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Efficient Liver Targeting by Polyvalent Display of a Compact Ligand for the Asialoglycoprotein Receptor.
Sanhueza, Carlos A; Baksh, Michael M; Thuma, Benjamin; Roy, Marc D; Dutta, Sanjay; Préville, Cathy; Chrunyk, Boris A; Beaumont, Kevin; Dullea, Robert; Ammirati, Mark; Liu, Shenping; Gebhard, David; Finley, James E; Salatto, Christopher T; King-Ahmad, Amanda; Stock, Ingrid; Atkinson, Karen; Reidich, Benjamin; Lin, Wen; Kumar, Rajesh; Tu, Meihua; Menhaji-Klotz, Elnaz; Price, David A; Liras, Spiros; Finn, M G; Mascitti, Vincent.
Afiliação
  • Sanhueza CA; School of Chemistry & Biochemistry, Georgia Institute of Technology , 901 Atlantic Avenue, Atlanta, Georgia 30332, United States.
  • Baksh MM; Department of Chemistry and The Skaggs Institute for Chemical Biology, The Scripps Research Institute , 10550 N. Torrey Pines Road, La Jolla, California 92037, United States.
  • Thuma B; School of Chemistry & Biochemistry, Georgia Institute of Technology , 901 Atlantic Avenue, Atlanta, Georgia 30332, United States.
  • Roy MD; Department of Chemistry and The Skaggs Institute for Chemical Biology, The Scripps Research Institute , 10550 N. Torrey Pines Road, La Jolla, California 92037, United States.
  • Dutta S; Pfizer Medicine Design , Eastern Point Road, Groton, Connecticut 06340, United States.
  • Préville C; Pfizer Drug Safety R&D , Eastern Point Road, Groton, Connecticut 06340, United States.
  • Chrunyk BA; Department of Chemistry and The Skaggs Institute for Chemical Biology, The Scripps Research Institute , 10550 N. Torrey Pines Road, La Jolla, California 92037, United States.
  • Beaumont K; Pfizer Medicine Design , Eastern Point Road, Groton, Connecticut 06340, United States.
  • Dullea R; Pfizer Medicine Design , Eastern Point Road, Groton, Connecticut 06340, United States.
  • Ammirati M; Pfizer Medicine Design , Main Street, Cambridge, Massachusetts 02139, United States.
  • Liu S; Pfizer CVMET Biology , Main Street, Cambridge, Massachusetts 02139, United States.
  • Gebhard D; Pfizer Medicine Design , Eastern Point Road, Groton, Connecticut 06340, United States.
  • Finley JE; Pfizer Medicine Design , Eastern Point Road, Groton, Connecticut 06340, United States.
  • Salatto CT; Pfizer Medicine Design , Eastern Point Road, Groton, Connecticut 06340, United States.
  • King-Ahmad A; Pfizer Drug Safety R&D , Eastern Point Road, Groton, Connecticut 06340, United States.
  • Stock I; Pfizer CVMET Biology , Main Street, Cambridge, Massachusetts 02139, United States.
  • Atkinson K; Pfizer Medicine Design , Eastern Point Road, Groton, Connecticut 06340, United States.
  • Reidich B; Pfizer Medicine Design , Eastern Point Road, Groton, Connecticut 06340, United States.
  • Lin W; Pfizer Medicine Design , Eastern Point Road, Groton, Connecticut 06340, United States.
  • Kumar R; Pfizer CVMET Biology , Main Street, Cambridge, Massachusetts 02139, United States.
  • Tu M; Pfizer Medicine Design , Eastern Point Road, Groton, Connecticut 06340, United States.
  • Menhaji-Klotz E; Pfizer Medicinal Sciences , Eastern Point Road, Groton, Connecticut 06340, United States.
  • Price DA; Pfizer Medicine Design , Main Street, Cambridge, Massachusetts 02139, United States.
  • Liras S; Pfizer Medicine Design , Main Street, Cambridge, Massachusetts 02139, United States.
  • Finn MG; Pfizer Medicine Design , Main Street, Cambridge, Massachusetts 02139, United States.
  • Mascitti V; Pfizer Medicine Design , Main Street, Cambridge, Massachusetts 02139, United States.
J Am Chem Soc ; 139(9): 3528-3536, 2017 03 08.
Article em En | MEDLINE | ID: mdl-28230359
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Polímeros / Compostos Bicíclicos com Pontes / Hepatócitos / Receptor de Asialoglicoproteína / Cetonas / Fígado Limite: Humans Idioma: En Ano de publicação: 2017 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Polímeros / Compostos Bicíclicos com Pontes / Hepatócitos / Receptor de Asialoglicoproteína / Cetonas / Fígado Limite: Humans Idioma: En Ano de publicação: 2017 Tipo de documento: Article