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A variant Sp1 (R218Q) transcription factor might enhance HbF expression in ß0 -thalassaemia homozygotes.
Jiang, Zhihua; Luo, Hong-Yuan; Farrell, John J; Zhang, Zhengjian; Schulz, Vincent P; Albarawi, Dilan; Steinberg, Martin H; Al-Allawi, Nasir A S; Gallagher, Patrick G; Forget, Bernard G; Chui, David H K.
Afiliação
  • Jiang Z; Departments of Medicine, Pathology and Laboratory Medicine, Boston University School of Medicine, Boston, MA, USA.
  • Luo HY; Departments of Medicine, Pathology and Laboratory Medicine, Boston University School of Medicine, Boston, MA, USA.
  • Farrell JJ; Departments of Medicine, Pathology and Laboratory Medicine, Boston University School of Medicine, Boston, MA, USA.
  • Zhang Z; Transcription Imaging Consortium, Janelia Research Campus, Howard Hughes Medical Institute, Ashburn, VA, USA.
  • Schulz VP; Departments of Pediatrics, Pathology, Genetics, Yale University School of Medicine, New Haven, CT, USA.
  • Albarawi D; Scientific Research Centre, College of Science, University of Duhok, Duhok, Iraq.
  • Steinberg MH; Departments of Medicine, Pathology and Laboratory Medicine, Boston University School of Medicine, Boston, MA, USA.
  • Al-Allawi NAS; Department of Pathology and Scientific Research Centre, College of Medicine, University of Duhok, Duhok, Iraq.
  • Gallagher PG; Departments of Pediatrics, Pathology, Genetics, Yale University School of Medicine, New Haven, CT, USA.
  • Forget BG; Departments of Medicine, Genetics, Yale University School of Medicine, New Haven, CT, USA.
  • Chui DHK; Departments of Medicine, Pathology and Laboratory Medicine, Boston University School of Medicine, Boston, MA, USA.
Br J Haematol ; 180(5): 755-757, 2018 03.
Article em En | MEDLINE | ID: mdl-28240767
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Hemoglobina Fetal / Fator de Transcrição Sp1 / Talassemia beta / Polimorfismo de Nucleotídeo Único / Mutação Limite: Adult / Humans / Male Idioma: En Ano de publicação: 2018 Tipo de documento: Article
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Hemoglobina Fetal / Fator de Transcrição Sp1 / Talassemia beta / Polimorfismo de Nucleotídeo Único / Mutação Limite: Adult / Humans / Male Idioma: En Ano de publicação: 2018 Tipo de documento: Article