Antimicrobial activity of 2-mercaptobenzothiazole released from environmentally friendly nanostructured layered double hydroxides.
J Appl Microbiol
; 122(5): 1207-1218, 2017 May.
Article
em En
| MEDLINE
| ID: mdl-28251734
ABSTRACT
AIMS:
The objective of this work was to assess the antibacterial effect of 2-mercaptobenzothiazole (MBT), used as model-biocide, immobilized in a layered double hydroxide (LDH) structure, under different conditions of pH and salinity, envisaging possible applications of the system in active antifouling and anticorrosion coatings. METHODS ANDRESULTS:
Biological effects of MBT immobilized in LDH were assessed by monitoring bacterial bioluminescence of cell suspensions of either Allivibrio fischeri or a recombinant strain of Escherichia coli, as a proxy for bacterial activity. Salinity (1, 2 and 3% NaCl) and pH (4, 5, 6 and 7) of the suspension media were experimentally manipulated and biocide release tests were performed in parallel. The release profiles obtained by UV-visible spectrophotometry indicated a fast release of biocide from MBT@LDH, slightly enhanced in 3% NaCl and under alkaline conditions. However, biological effects were more pronounced at 1% NaCl and at neutral pH.CONCLUSIONS:
The release and toxic effect of MBT immobilized in LDH is dependent on the concentration of solutes in the suspension medium. SIGNIFICANCE AND IMPACT OF THE STUDY The results confirm LDH as a biologically compatible material with potential to be used for biocide delivery.Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Benzotiazóis
/
Hidróxidos
/
Antibacterianos
Idioma:
En
Ano de publicação:
2017
Tipo de documento:
Article