Ethyl acetate extract from Asparagus cochinchinensis exerts anti­inflammatory effects in LPS­stimulated RAW264.7 macrophage cells by regulating COX­2/iNOS, inflammatory cytokine expression, MAP kinase pathways, the cell cycle and anti-oxidant activity.

Lee, Hyun Ah; Koh, Eun Kyoung; Sung, Ji Eun; Kim, Ji Eun; Song, Sung Hwa; Kim, Dong Seob; Son, Hong Joo; Lee, Chung Yeoul; Lee, Hee Seob; Bae, Chang Joon; Hwang, Dae Youn

Ethyl acetate extract from Asparagus cochinchinensis exerts antiinflammatory effects in LPSstimulated RAW264.7 macrophage cells by regulating COX2/iNOS, inflammatory cytokine expression, MAP kinase pathways, the cell cycle and anti-oxidant activity.

Lee, Hyun Ah; Koh, Eun Kyoung; Sung, Ji Eun; Kim, Ji Eun; Song, Sung Hwa; Kim, Dong Seob; Son, Hong Joo; Lee, Chung Yeoul; Lee, Hee Seob; Bae, Chang Joon; Hwang, Dae Youn.

Afiliação

Lee HA; College of Natural Resources and Life Science/Life and Industry Convergence Research Institute, Pusan National University, Miryang, Gyeongsangnamdo 627706, Republic of Korea.
Koh EK; College of Natural Resources and Life Science/Life and Industry Convergence Research Institute, Pusan National University, Miryang, Gyeongsangnamdo 627706, Republic of Korea.
Sung JE; College of Natural Resources and Life Science/Life and Industry Convergence Research Institute, Pusan National University, Miryang, Gyeongsangnamdo 627706, Republic of Korea.
Kim JE; College of Natural Resources and Life Science/Life and Industry Convergence Research Institute, Pusan National University, Miryang, Gyeongsangnamdo 627706, Republic of Korea.
Song SH; College of Natural Resources and Life Science/Life and Industry Convergence Research Institute, Pusan National University, Miryang, Gyeongsangnamdo 627706, Republic of Korea.
Kim DS; College of Natural Resources and Life Science/Life and Industry Convergence Research Institute, Pusan National University, Miryang, Gyeongsangnamdo 627706, Republic of Korea.
Son HJ; College of Natural Resources and Life Science/Life and Industry Convergence Research Institute, Pusan National University, Miryang, Gyeongsangnamdo 627706, Republic of Korea.
Lee CY; Gangrim Organics, Miryang, Gyeongsangnamdo 627706, Republic of Korea.
Lee HS; College of Human Ecology, Pusan National University, Busan 609735, Republic of Korea.
Bae CJ; Biologics Division, Ministry of Food and Drug Safety, Cheongju, Chungcheongbukdo 361951, Republic of Korea.
Hwang DY; College of Natural Resources and Life Science/Life and Industry Convergence Research Institute, Pusan National University, Miryang, Gyeongsangnamdo 627706, Republic of Korea.

Mol Med Rep ; 15(4): 1613-1623, 2017 Apr.

Article em En | MEDLINE | ID: mdl-28260011

Assuntos

Anti-Inflamatórios/farmacologia; Asparagus/química; Ciclo Celular/efeitos dos fármacos; Ciclo-Oxigenase 2/metabolismo; Citocinas/metabolismo; Macrófagos/metabolismo; Óxido Nítrico Sintase Tipo II/metabolismo; Extratos Vegetais/farmacologia; Acetatos/química; Animais; Antioxidantes/metabolismo; Sequestradores de Radicais Livres/farmacologia; Mediadores da Inflamação/metabolismo; Lipopolissacarídeos; Sistema de Sinalização das MAP Quinases/efeitos dos fármacos; Macrófagos/efeitos dos fármacos; Camundongos; Óxido Nítrico/biossíntese; Células RAW 264.7; Espécies Reativas de Oxigênio/metabolismo

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Extratos Vegetais / Ciclo Celular / Citocinas / Asparagus / Ciclo-Oxigenase 2 / Óxido Nítrico Sintase Tipo II / Macrófagos / Anti-Inflamatórios Limite: Animals Idioma: En Ano de publicação: 2017 Tipo de documento: Article

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