NF1-mutated melanoma tumors harbor distinct clinical and biological characteristics.

Cirenajwis, Helena; Lauss, Martin; Ekedahl, Henrik; Törngren, Therese; Kvist, Anders; Saal, Lao H; Olsson, Håkan; Staaf, Johan; Carneiro, Ana; Ingvar, Christian; Harbst, Katja; Hayward, Nicholas K; Jönsson, Göran

Cirenajwis, Helena; Lauss, Martin; Ekedahl, Henrik; Törngren, Therese; Kvist, Anders; Saal, Lao H; Olsson, Håkan; Staaf, Johan; Carneiro, Ana; Ingvar, Christian; Harbst, Katja; Hayward, Nicholas K; Jönsson, Göran.

Afiliação

Cirenajwis H; Division of Oncology and Pathology, Department of Clinical Sciences, Lund University, Sweden.
Lauss M; Division of Oncology and Pathology, Department of Clinical Sciences, Lund University, Sweden.
Ekedahl H; Division of Surgery, Department of Clinical Sciences, Lund University, Sweden.
Törngren T; Division of Oncology and Pathology, Department of Clinical Sciences, Lund University, Sweden.
Kvist A; Division of Oncology and Pathology, Department of Clinical Sciences, Lund University, Sweden.
Saal LH; Division of Oncology and Pathology, Department of Clinical Sciences, Lund University, Sweden.
Olsson H; Division of Oncology and Pathology, Department of Clinical Sciences, Lund University, Sweden.
Staaf J; Department of Oncology, Skåne University Hospital, Lund University, Sweden.
Carneiro A; Division of Oncology and Pathology, Department of Clinical Sciences, Lund University, Sweden.
Ingvar C; Division of Oncology and Pathology, Department of Clinical Sciences, Lund University, Sweden.
Harbst K; Department of Oncology, Skåne University Hospital, Lund University, Sweden.
Hayward NK; Division of Surgery, Department of Clinical Sciences, Lund University, Sweden.
Jönsson G; Division of Oncology and Pathology, Department of Clinical Sciences, Lund University, Sweden.

Mol Oncol ; 11(4): 438-451, 2017 04.

Article em En | MEDLINE | ID: mdl-28267273

Assuntos

Melanoma/genética; Melanoma/patologia; Mutação/genética; Neurofibromina 1/genética; Adulto; Idoso; Idoso de 80 Anos ou mais; Estudos de Coortes; Feminino; Genoma Humano; Humanos; Sistema de Sinalização das MAP Quinases/genética; Masculino; Melanoma/enzimologia; Pessoa de Meia-Idade; Análise de Sobrevida

Palavras-chave

BRAF; NRAS; NF1; melanoma

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neurofibromina 1 / Melanoma / Mutação Tipo de estudo: Etiology_studies / Incidence_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limite: Adult / Aged / Aged80 / Female / Humans / Male / Middle aged Idioma: En Ano de publicação: 2017 Tipo de documento: Article

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