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Small molecule inhibitors block Gas6-inducible TAM activation and tumorigenicity.
Kimani, Stanley G; Kumar, Sushil; Bansal, Nitu; Singh, Kamalendra; Kholodovych, Vladyslav; Comollo, Thomas; Peng, Youyi; Kotenko, Sergei V; Sarafianos, Stefan G; Bertino, Joseph R; Welsh, William J; Birge, Raymond B.
Afiliação
  • Kimani SG; Rutgers University, New Jersey Medical School, Department of Microbiology, Biochemistry and Molecular Genetics, Cancer Center, 205 South Orange Ave, Newark, NJ 07103, USA.
  • Kumar S; Rutgers University, New Jersey Medical School, Department of Microbiology, Biochemistry and Molecular Genetics, Cancer Center, 205 South Orange Ave, Newark, NJ 07103, USA.
  • Bansal N; Rutgers University, Cancer Institute of New Jersey, 195 Little Albany Street, New Brunswick, NJ 08903, USA.
  • Singh K; Department of Molecular Microbiology and Immunology, and Department of Biochemistry, Bond Life Sciences Center, University of Missouri, Columbia, MO 65211, USA.
  • Kholodovych V; Rutgers University, Office of Advanced Research Computing, 96 Frelinghuysen Road, Piscataway, NJ 08854, USA.
  • Comollo T; Rutgers University, Robert Wood Johnson Medical Center, Department of Pharmacology, 675 Hoes Lane, Piscataway, NJ 08854, USA.
  • Peng Y; Rutgers University, New Jersey Medical School, Department of Microbiology, Biochemistry and Molecular Genetics, Cancer Center, 205 South Orange Ave, Newark, NJ 07103, USA.
  • Kotenko SV; Rutgers University, Cancer Institute of New Jersey, 195 Little Albany Street, New Brunswick, NJ 08903, USA.
  • Sarafianos SG; Rutgers University, New Jersey Medical School, Department of Microbiology, Biochemistry and Molecular Genetics, Cancer Center, 205 South Orange Ave, Newark, NJ 07103, USA.
  • Bertino JR; Department of Molecular Microbiology and Immunology, and Department of Biochemistry, Bond Life Sciences Center, University of Missouri, Columbia, MO 65211, USA.
  • Welsh WJ; Rutgers University, Cancer Institute of New Jersey, 195 Little Albany Street, New Brunswick, NJ 08903, USA.
  • Birge RB; Rutgers University, Cancer Institute of New Jersey, 195 Little Albany Street, New Brunswick, NJ 08903, USA.
Sci Rep ; 7: 43908, 2017 03 08.
Article em En | MEDLINE | ID: mdl-28272423
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Piperazinas / Proteínas Proto-Oncogênicas / Receptores Proteína Tirosina Quinases / Peptídeos e Proteínas de Sinalização Intercelular / Inibidores de Proteínas Quinases / Carcinogênese / C-Mer Tirosina Quinase / Isoxazóis Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Ano de publicação: 2017 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Piperazinas / Proteínas Proto-Oncogênicas / Receptores Proteína Tirosina Quinases / Peptídeos e Proteínas de Sinalização Intercelular / Inibidores de Proteínas Quinases / Carcinogênese / C-Mer Tirosina Quinase / Isoxazóis Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Ano de publicação: 2017 Tipo de documento: Article