Oxidative stress elicited by modifying the ceramide acyl chain length reduces the rate of clathrin-mediated endocytosis.

Volpert, Giora; Ben-Dor, Shifra; Tarcic, Ohad; Duan, Jingjing; Saada, Ann; Merrill, Alfred H; Pewzner-Jung, Yael; Futerman, Anthony H

Volpert, Giora; Ben-Dor, Shifra; Tarcic, Ohad; Duan, Jingjing; Saada, Ann; Merrill, Alfred H; Pewzner-Jung, Yael; Futerman, Anthony H.

Afiliação

Volpert G; Department of Biomolecular Sciences, Weizmann Institute of Science, Rehovot 76100, Israel.
Ben-Dor S; Department of Biological Services, Weizmann Institute of Science, Rehovot 76100, Israel.
Tarcic O; Department of Molecular Cell Biology, Weizmann Institute of Science, Rehovot 76100, Israel.
Duan J; School of Biology and Petit Institute for Bioengineering and Bioscience, Georgia Institute of Technology, Atlanta, GA 30332-0230, USA.
Saada A; Monique and Jacques Roboh Department of Genetic Research, Hadassah-Hebrew University Hospital, Jerusalem 91120, Israel.
Merrill AH; The Department of Genetic and Metabolic Diseases, Hadassah-Hebrew University Hospital, Jerusalem 91120, Israel.
Pewzner-Jung Y; School of Biology and Petit Institute for Bioengineering and Bioscience, Georgia Institute of Technology, Atlanta, GA 30332-0230, USA.
Futerman AH; Department of Biomolecular Sciences, Weizmann Institute of Science, Rehovot 76100, Israel.

J Cell Sci ; 130(8): 1486-1493, 2017 04 15.

Article em En | MEDLINE | ID: mdl-28280117

Assuntos

Astrócitos/fisiologia; Ceramidas/metabolismo; Endocitose; Fígado/fisiologia; Estresse Oxidativo/imunologia; Esfingolipídeos/metabolismo; Esfingosina N-Aciltransferase/metabolismo; Animais; Membrana Celular/metabolismo; Células Cultivadas; Ceramidas/química; Clatrina/metabolismo; Endocitose/genética; Camundongos; Camundongos Knockout; Estresse Oxidativo/genética; Engenharia de Proteínas; Transdução de Sinais; Esfingosina N-Aciltransferase/genética

Palavras-chave

Clathrin-mediated endocytosis; Hsc70; Reactive oxygen species; Sp1; Very long-chain ceramides

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Esfingolipídeos / Ceramidas / Astrócitos / Estresse Oxidativo / Endocitose / Esfingosina N-Aciltransferase / Fígado Limite: Animals Idioma: En Ano de publicação: 2017 Tipo de documento: Article

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google